The oral lichen planus constitutes one of the white injuries more frequent than they appear in the oral mucosa and it is considered that it has certain risk of malignant transformation, recognising the presence of epithelial dysplasia like predicting histological of these changes. The occurrence of epithelial dysplasia, as a possible precursor of malignant transformation, has been studied scarc...

BACKGROUND The oral mucosa is constantly exposed to several irritants and allergens including dental materials, but the role of contact allergy in oral disease is obscure. OBJECTIVE To analyze positive patch test results in patients with oral diseases and evaluate the clinical relevance of oral diseases with contact allergy to dental materials. METHODS We retrospectively analyzed patch test...

Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa which is considered by the World Health Organization (WHO) as a premalignant condition. One step in malignant development is so called epithelial mesenchymal transition (EMT), a process whereby epithelial cells acquire mesenchymal characteristics. A factor known to induce EMT is the transforming growth factor-β (TGF-β...

Dysphagia is not uncommon in gastroenterology practice. The differential diagnosis is wide and includes both mechanical and motility causes. Esophageal lichen planus is uncommon but now increasingly recognized. It occurs in more than half of cases of lichen planus with muco-cutaneous involvement. Often there is a delay in diagnosis and subsequent treatment. The endoscopic picture of esophageal ...

Objectives: Studies done on the management of oral lichen planus using tacrolimus are limited. The aim of the study is to compare the efficacy of tacrolimus with triamcinolone acetonide topically in the management of symptomatic oral lichen planus and also to evaluate adverse effects and opportunistic yeast infections. Materials and methods: A randomized controlled study was conducted on 60 pat...

Objective. Oral exfoliative cytology (OEC) has been implemented in the diagnosis of pathologic lesions for ages. The present study was undertaken to evaluate the cytomorphological features of some of the commonest potentially malignant disorders (leukoplakia, lichen planus, and oral submucous fibrosis) through a simple procedure and illustrate its importance in mass screening. Materials and Met...

Physical examination There were multiple ulcerations over the lower lip (Figure 1). The gingiva was swollen and inflamed (Figure 1). Lace-like whitish streaks and well-defined Date: 13 March, 2002 Venue: Yaumatei Dermatology Clinic Organizer: Social Hygiene Service, DH; Clinico-pathological Seminar whitish plaques were found on the lower lip, gingiva and the left buccal mucosa (Figures 1& 2). T...

Chronic ulcerative dermatitis (CUS) is characterized by painful exacerbating and remitting oral erosions and ulcerations. A very characteristic direct immunofluorescence (DIF) pattern differentiates CUS from other immune-mediated oral vesiculo-erosive conditions. The clinical and histopathological features of CUS are very similar to erosive oral lichen planus. A middle-aged woman had CUS confir...

FDG: fluorodeoxyglucose LPP: lichen planopilaris PET-CT: positron emission tomographye computed tomography PD-1: programmed cell death receptor 1 P embrolizumab, a programmed cell death receptor 1 (PD-1) inhibitor, has been used effectively for treatment of metastatic melanoma. Reported cutaneous adverse events ascribed to PD-1 inhibitors include lichenoid reactions such as lichen planus of the...

OBJECTIVES To determine contact allergies in patients with oral lichen planus and to monitor the effect of partial or complete replacement of amalgam fillings following a positive patch test reaction to ammoniated mercury, metallic mercury, or amalgam. DESIGN In group A (20 patients), the oral lesions were confined to areas in close contact with amalgam fillings. In group B (20 patients), the...