Squamous cell carcinoma of the oral cavity is one of the most prevalent tumors of the head and neck region. Despite an ever-expanding fund of knowledge regarding the etiology and pathophysiology of malignant neoplasms, oral squamous cell carcinoma (OSCC) continues to be a disfiguring and deadly disease. For patients with squamous cell carcinoma of the oral cavity or oropharynx, the 5-year survi...

osteosarcoma is relatively rare in the jaws and variable in presentation, thus its recognition may be quite confusing and delay diagnosis and treatment. also, in contrast to most malignancies, osteosarcoma is usually encountered earlier in life and may clinically resemble features of more common oral entities such as chronic osteomyelitis, fibrous dysplasia, osteoblastic metastatic carcinoma, o...

UNLABELLED Oral squamous cells carcinoma (OSCC) shows unfavorable prognosis due to its invasion potential around the neighboring tissues and the elevated incidence of metastasis. AIM the present paper aims at analyzing the immunohistochemical expression of the nm23 protein in metastatic and non-metastatic SCCs of tongue. METHODS the immuno-expression to the nm23-hl protein was diagnosed in ...

BACKGROUND Extramedullary myelomas (plasmacytoma) are malignant proliferations of plasma cells in the absence of bone involvement. When they occur in the soft tissue they usually involve the upper respiratory tract and oral cavity. Extramedullary plasmacytomas of breast are uncommon. CASE PRESENTATION A 70 year-old woman with bilateral breast masses underwent excisional biopsy for suspected p...

Metastatic adenocarcinoma to the liver from an unidentified primary tumor site is a common diagnostic problem. The present study included 41 cases of histologically diagnosed liver biopsies including hepatocellular carcinoma, cholangiocarcinoma and metastatic carcinoma in the liver. All cases were stained immunohistochemically with Cytokeratin 18, 7, and 20, Carbohydrate Antigen 19-9 and Alpha-...

Introduction Parotid gland squamous cell carcinoma is an uncommon aggressive neoplasm with poor prognosis. Aural polyps are usually the presenting features of chronic suppurative otitis media, tuberculous otitis media, and adenoma or carcinoma. The malignant aural polyp is very rare. Parotid gland carcinoma masquerading as an aural polyp has rarely been described in the literature. ...

background and aim: squamous cell carcinoma is the eighth common cancer and forms 94% of oral malignancies. nowadays, many molecular and genetic changes have been known to affect tumoral behavior which might be good for drug production and gene therapy. it has been known that mutated p53, overexpression of p63 as an oncogene and hpv infection are correlated with clinicopathological behavior of ...