The immune system in the gastrointestinal tract plays a crucial role in the control of infection, as it constitutes the first line of defense against mucosal pathogens. The attractive features of oral immunization have led to the exploration of a variety of oral delivery systems. However, none of these oral delivery systems have been applied to existing commercial vaccines. To overcome this, a ...

Nutraceutical is a food or à food ingredient that provides medical and health benefits. Polyphenols play an important role in the maintenance of health and prevention of diseases. Among polyphenols, the most widely used substance Curcumin. Curcumin derived from the herbal remedy and dietary spice turmeric. It possesses wide range of beneficial properties includes anti-inflammatory, anti-oxidant...

Sorafenib, a multikinase inhibitor used for the treatment of hepatocellular carcinoma, is limited by its low oral bioavailability. To overcome this drawback, we have developed novel camel milk casein-derived nanoparticles as drug delivery system. Camel casein not only biocompatible on administration but actually dietary protein pharmaceutical relevance. Casein because amphiphilic nature, self-a...

Peptides and proteins play an essential role in biological systems the human body. Deficiency or dysfunction of peptides such as insulin can lead to various illnesses. The therapeutic use some illnesses diabetes, cardiovascular disease, autoimmunity, cancer, among others, is highly considered. have large molecular structures are generally hydrophilic, maintaining their spatial composition terti...

Absorption of drugs through the oral cavity was noted as early as 1847 and systemic studies of oral cavity absorption were first reported in 1935 [1]. Since then, substantial effort has been focused on drug absorption from a drug delivery system in a particular region of the oral cavity [2-5]. As a site for drug delivery, the oral cavity offers many advantages over other routes of drug administ...

The oral route for drug delivery is regarded as the optimal route for achieving therapeutic benefits owing to increased patient compliance. Despite phenomenal advances in injectable, transdermal, nasal and other routes of administration, the reality is that oral drug delivery remains well ahead of the pack as the preferred delivery route. Nanocarriers can overcome the major challenges associate...