A two-phase approach to dynamic combinatorial chemistry is described using disulfide exchange chemistry; the use of two phases significantly increases the possibilities and the scope of dynamic combinatorial chemistry by facilitating the combination of otherwise incompatible building blocks.

Synthesis 2003, No. 7, Print: 20 05 2003. Art Id.1437-210X,E;2003,0,07,0961,1008,ftx,en;E08002SS.pdf. © Georg Thieme Verlag Stuttgart · New York Abstract: The synthesis of new complex structures is still a challenge in preparative organic chemistry. Focusing on the generation of defined stereogenic centers, the [3,3]-sigmatropic rearrangements are known as reliable reactions. Always, a highly o...

We propose an efficient protocol for digital quantum simulation of quantum chemistry problems and enhanced digital-analog quantum simulation of transport phenomena in biomolecules with superconducting circuits. Along these lines, we optimally digitize fermionic models of molecular structure with single-qubit and two-qubit gates, by means of Trotter-Suzuki decomposition and Jordan-Wigner transfo...

The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic syn...

Mehmet A. OTURAN, Maurice MÉDEBIELLE Université Paris 7 Denis Diderot, Laboratoire d’Electrochimie Moléculaire, UMR CNRS 7591, Case courrier 7107, 2 Place Jussieu, 75251 Paris Cedex 05-FRANCE e-mail: [email protected] Shirish A. PATIL, Robert S. KLEIN Albert Einstein College of Medicine Cancer Centre and Medicinal Chemistry Laboratory, Department of Oncology, Montefiore Medical Centre, Bronx, ...

We highlight chemistry and trend measurement results from the Atmospheric Chemistry Experiment (ACE) which is providing precise middle troposphere to the lower thermosphere measurements with a 0.02 cm resolution Fourier transform spectrometer covering 750-4400 cm.

The year 1970 has been suggested as a starting date for the "third age of quantum chemistry," in which theory takes on not only qualitative but also quantitative value. In fact, each of the years 1960, 1970, 1972, and 1977 is of historical value in the unraveling of the structure and energetics of the CH(2) molecule, methylene. What took place for methylene, namely the establishment of credibil...

1 Department of Biological Sciences, Purdue University, West Lafayette, IN, United States, 2 Bindley Bioscience Center, Purdue University, West Lafayette, IN, United States, 3 Purdue Institute for Drug Discovery, Purdue University, West Lafayette, IN, United States, 4 Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States, 5 Purdue Ins...