Pesticide exposure has been implicated in the etiopathogenesis of Parkinson's disease (PD); in particular, the organochlorine insecticide dieldrin is believed to be associated with PD. Emerging evidence indicates that histone modifications play a critical role in cell death. In this study, we examined the effects of dieldrin treatment on histone acetylation and its role in dieldrin-induced apop...

Concentrations of the organochlorine pesticides hexachlorobenzene (HCB), gamma-hexachlorocyclohexane (gamma-HCH), DDT and its metabolite p,p'-dichlorodiphenyldichloroethylene (DDE), and seven polychlorinated biphenyl (PCB) congeners were analyzed in livers and adipose tissue samples of 145 white-tailed eagles found dead or moribund in Germany from 1979 to 2001. Most birds were found in the regi...

background: chlorinated pesticides have been used in pest control for several decades in the world. these compounds are still applied in many regions, and their continuous usage has resulted in their bioaccumulation and residue in the food chain. these residues could transfer to food products and accumulate in fat tissues. undoubtedly, the breast milk could be a significant biomarker for estima...

AIMS To assess the association between prenatal exposure to organochlorine compounds and thyroid status in newborns from an area with high levels of hexachlorobenzene (HCB). METHODS A total of 98 mother-infant pairs (83.1% of all children born during the period 1997-99 in a specific area polluted with HCB) were recruited. Levels of organochlorine compounds were measured in 70 cord serum sampl...

the aim of this study was to determine the environmental risk of pesticide a.i. applied to control insects and fungus in cereal farming in sanliurfa, turkey. in 2013, 8 active ingredients (a.i.) in cereal farming were applied for insect and fungus control in sanliurfa, turkey. these a.i. were alpha-cypermethrin(ec), chlorpyrifos(ec;wp), difenoconazole(ec), indoxacarb(wg), lambda-cyhalothrin(ec)...

BACKGROUND Persistent organic pollutants represent about 95 % of the industrial sector effluents in Egypt. Contamination of the River Nile water with various pesticides poses a hazardous risk to both human and environmental compartments. Therefore, a large scale monitoring study was carried on pesticides pollution in three geographical main regions along the River Nil water stream, Egypt. MET...

The Tibetan Plateau (TP) has been contaminated by persistent organic pollutants (POPs), including legacy organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) through atmospheric transport. The exact source regions, transport pathways and time trends of POPs to the TP are not well understood. Here polystyrene– divinylbenzene copolymer resin (XAD)-based passive air samplers (PASs...

The organochlorine pesticides (OP) are very stable molecules, due to this stability; they are very resistant in the environment and highly related to fat tissues with a wide diffusion property and an average time life higher then 10 years. We studied sediments (November 2001, April and June 2002) and organisms collected in April and July (2002) from the lacustric zone of Metzitlán, Hidalgo, Mex...

Polychlorobiphenyls (PCBs), polybromodiphenylethers (PBDEs) and organochlorine pesticides (OCPs), such as dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB), are considered as endocrine disruptors in laboratory and wild animals. This study investigated whether these compounds and their hydroxylated metabolites (HO-PCBs and HO-PBDEs) may affect the homoeostasis of vitamin A, a die...