Studies have identified the risk factors like folic acid deficiency during gestational period, family history for orofacial clefts, drugs like antiepileptic, vitamin A. But, the data regarding the folic acid status in children with cleft lip/palate is hardly evaluated in depth. Here, an assessment of folic acid and DNA damage were carried out in children with orofacial anomalies. Folic acid lev...

Objective: To investigate and compare stress and satisfaction with motherhood of mothers of children with versus without an orofacial cleft. Setting: Cleft palate center and a child day care in Amsterdam, The Netherlands. Participants: Seventy six mothers with children aged 0-4 years with clefts were included. The children were treated at the academic cleft palate center in Amsterdam, The Nethe...

BACKGROUND Orofacial clefts are usually isolated cases but can be associated with other congenital malformations that are either recognised or unrecognised syndromes. The reported prevalence and pattern of such associated malformations, however, vary among studies. OBJECTIVES To assess the frequencies and aetiologies of congenital malformations and associated medical conditions in children wi...

UNLABELLED Background Several studies have examined the effects of folic acid fortification on the occurrence of orofacial clefts. This study was carried out to evaluate the impact of flour fortification with folic acid on oral clefts in Northern Iran. METHODS In this hospital based study from March 2006 to September 2009, we screened the total number of live births at all hospitals in Golest...

INTRODUCTION Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnosti...