نتایج جستجو برای: orthomyxoviridae
تعداد نتایج: 8630 فیلتر نتایج به سال:
Increase in the number of acute respiratory infection cases was observed in the month of February 2002 at Pune, India. A total of 11 clinical samples were positive for influenza viral antigen and virus isolates were obtained from eight samples. Antigenic and genetic analyses of these isolates identified them to be similar to B/Beijing/243/97 belonging to the B/Victoria/2/87 lineage. B/Victoria/...
In the advent of an influenza virus pandemic it is likely that the administration of antiviral drugs will be an important first line of defence against the virus. The drugs currently in use are effective against seasonal influenza virus infection, and some cases have been used in the treatment of patients infected with the avian H5N1 influenza virus. However, it is becoming clear that the emerg...
Terence S. Dermody, Editor, Journal of Virology, Rozanne M. Sandri-Goldin, Editor-in-Chief, Journal of Virology, Thomas Shenk, Chair, ASM Journals Board Departments of Pediatrics and Pathology, Microbiology, and Immunology and Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee, USA; Department of Microbiology and Molecular Genetics, U...
Repeated transmission of animal influenza viruses to humans has prompted investigation of the viral, host, and environmental factors responsible for transmission via aerosols or respiratory droplets. How do we determine-out of thousands of influenza virus isolates collected in animal surveillance studies each year-which viruses have the potential to become 'airborne', and hence pose a pandemic ...
Like all viruses, influenza viruses (IAVs) use host translation machinery to decode viral mRNAs. IAVs ensure efficient translation of viral mRNAs through host shutoff, a process whereby viral proteins limit the accumulation of host proteins through subversion of their biogenesis. Despite its small genome, the virus deploys multiple host shutoff mechanisms at different stages of infection, there...
We retrospectively demonstrated that an outbreak of severe respiratory disease in a pack of English foxhounds in the United Kingdom in September 2002 was caused by an equine influenza A virus (H3N8). We also demonstrated that canine respiratory tissue possesses the relevant receptors for infection with equine influenza virus.
Van Baalen, C.A., C. Els, L. Sprong, R. van Beek, E. van der Vries, A.D.M.E. Osterhaus 6 and G.F. Rimmelzwaan 7 1 Viroclinics Biosciences, Rotterdam, The Netherlands; 2 Erasmus MC Department of 8 Viroscience, Rotterdam, The Netherlands. 9 10 # Address correspondence to: [email protected] 11 12 Institutional addresses: 13 Viroclinics Biosciences; Marconistraat 16; 3029 AK Rotterdam; The Net...
BACKGROUND Understanding the epidemiological dynamics of influenza virus is central to surveillance and vaccine strain selection. It has been suggested that tropical and subtropical regions represent the global source of influenza epidemics. However, our understanding of the epidemiological dynamics of influenza virus in these regions is limited by a relative lack of long-term data. METHODS W...
Primary CD8+ T cell (T(CD8+)) responses to viruses are directed toward multiple Ags and shaped by both the level of Ag presentation and the underlying Ag-specific T(CD8+) repertoire. The relative importance of these factors in deciding the hierarchy of T(CD8+) responses and how they are influenced by the immunoproteasome are not well understood. Using an influenza infection model in mice defici...
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