A study has been made of the effect of age on the susceptibility of mature human erythrocytes to hemolysis in hypotonic media. The alterations in osmotic fragility associated with red cell aging are pertinent to the relationship between cellular senescence and the maintenance of cell mambrane integrity. In addition, differences in osmotic resistance between young and old erythrocytes could prov...

We study the impact on financial fragility of globalization and a switch from managed to freely floating exchange rate regime in the context of a two-country multi-region model a la Allen and Gale (Journal of Political Economy, 2000) with open-economy monetary features of Chang and Velasco (Journal of Economic Theory, 2000). In this economy, both banking and exchange rate crises may develop. In...

Experiments were performed with the aim of investigating the effect of season on haematological parameters and erythrocyte osmotic fragility (EOF) of pigs. A total of 23 local pigs including males, non-pregnant and non-nursing females, aged 9 to 12 months were used for the study, ten animals were used during the hot-dry season and thirteen during the harmattan season. Blood sample was taken fro...

It is generally accepted that when erythrocytes are suspenided in hypotonic solutions thev first take up water and swell, and theni at some critical tonicity burst and allow hemoglobin to escape. While there are many indications that the permeability of these cells to both salts and water may vary considerably in different conditions (1, 2, 3), quantitative data on the osmometric behavior of ei...

The paper presents the data on percent lysis of hemoglobin in Tuberculosis patient’s blood. Osmotic fragility is the ability of RBC’s to resist rupture (lysis) in hypotonic saline. The degree of hemolysis can be estimated by measuring the colour intensity of the supernant in a spectrophotometer at 540nm and comparing it with 100%. The task is to examine the relationship between the extent of he...

It has been shown that red cells of blood collected in acid-citrate-dextrose (ACD) undergo changes in their dimensions, osmotic fragility, permeability and metabolism during storage at 4° C (1). Information concerning the effect of storage on the physical and chemical states of soluble red cell proteins, particularly hemoglobin, is not available. Such data may be of interest in view of the mark...

Enhanced oxidative stress is reported as one of the main determinants of aging and age related events. Several parameters of blood have been demonstrated to be negatively affected by increased oxidative stress including changes in erythrocyte membrane fluidity and integrity, which results into overall malfunctioned cellular physiology. Present study was aimed to determine the erythrocyte osmoti...