Zusammenfassung Das sozialistische Wirtschaftssystem der DDR brach 1990 zusammen. Nach Wiedervereinigung war es das Kernziel des Aufbaus Ost, einen Wirtschaftssektor in Ostdeutschland (der ehemaligen DDR) zu schaffen, im internationalen Wettbewerb bestehen kann. Die sozialistischen Betriebe wurden privatisiert oder geschlossen. Der Staat hat Investitionen durch Subventionen massiv gefördert. he...

BACKGROUND There is good evidence for the effectiveness of opioid substitution therapy (OST) for injecting drug users (IDUs) in middle and high-income countries but little evidence regarding the provision of OST by non-government organisations (NGOs) in resource-poor settings. This paper reports on outcomes of an NGO-based OST program providing sub-lingual buprenorphine to opiate dependent IDUs...

Background: Currently, there are no effective markers to diagnose and monitor patients with neuroendocrine tumors (NETs). The aim of this study was assess bone metabolism based on selected turnover: OST, OPG, IGFBP-3, in both the group NETs control group. Associations sociodemographic, biochemical, clinicopathological characteristics were examined. We also evaluated any potential associations b...

Chemical modification of biological molecules is a general mechanism for cellular regulation. A quantitative approach has been developed to measure the extent of modification on HS (heparan sulphates). Sulphation on HS by sulphotransferases leads to variable sulphation levels, which allows cells to tune their affinities to various extracellular proteins, including growth factors. With stable is...