نتایج جستجو برای: osteomalacia
تعداد نتایج: 1515 فیلتر نتایج به سال:
Osteoporosis is characterized by abnormal porosity and rarefaction of bone, resulting in decreased radiodensity. Albright defined osteoporosis as: "that category of decreased bone mass where the disturbance is the failure of the osteoblast to lay down bone matrix." He further stated that "Osteoporosis is a decreased production of osteoid by the osteoblasts, and is a defect in tissue metabolism....
UNLABELLED We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occ...
The characteristics triad of tuberous sclerosis-adenoma sebaceum, mental deficiency and epilepsy-associated with distal-type renal tubular acidosis was combined with anticonvulsant osteomalacia in a 41-year-old woman. In addition to the specific bone lesions of tuberous sclerosis, the bone disease was caused by an adverse effect of a drug and possibly also by the renal disorder leading to signi...
Vitamin D is now known to undergo 25-hydroxylation in the liver and subsequently 1 a-hydroxylation in the kidney to form 1,25dihydroxyvitamin D, (1,25(OH)2D), before exerting its biological effects.' This knowledge has stimulated investigation into possible therapeutic applications of vitamin D metabolites and their synthetic analogues in metabolic bone disease. 1 a-hydroxyvitamin D3 (1 ocOHD3)...
The detailed study of a battery plate maker, who had worked with cadmium for 36 years, showed that proteinuria, typical of renal tubular dysfunction, had been observed for 25 years and during the last 12 years of his life the patient had suffered increasing disability from gross bone disease. Several bone biopsies and detailed metabolic studies showed typical severe osteomalacia, which responde...
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