Osteonecrosis of the jaw (ONJ) is a common side effect of antiresorptive drugs that are administered to cancer patients for bone metastasis, multiple myeloma, and osteoporosis. Since both bisphosphonate (BP) and denosumab show anti-bone resorption effects with ONJ, antiresorptive agent-related ONJ (ARONJ) has been suggested as a comprehensive term encompassing both BP-related osteonecrosis of t...

Dott. Massimo Bertoli, Riviera S. Benedetto, 124, I-35100 Padova (Italy) Dear Sir, Aseptic osteonecrosis of the femur head, a disabling disease which strikes about 16% of renal transplant recipients, seems clearly related to steroid therapy as its incidence drops sharply with the use of new immunosuppres-sants such as cyclosporin [1]. Several etiological factors related to corticosteroid treatm...

Untreated osteonecrosis of the femoral head ultimately leads to collapse and disintegration of hip joint. The predegenerative stages of osteonecrosis especially when seen in young adults, should be treated by a femoral head preservation operation with the objective to delay and possibly to avert the above consequences. Previously head preserving surgeries were not in vogue so total hip replacem...

Osteonecrosis of the femoral head is an intractable disease often occurring in patients aged 30-40 years that can cause femoral head collapse, pain, and gait disturbance. Background factors, including corticosteroid use, alcohol intake, and idiopathic causes, have been indicated. It is estimated that 70-80 % of osteonecrosis patients experience femoral head collapse, for which total hip arthrop...

Recent reports have shown successful transfer of vascularized fibular flap in bisphosphonate-induced mandibular osteonecrosis. We present a case of a 50-year-old patient who presented with bisphosphonate-related osteonecrosis of bilateral maxilla, which is reconstructed using a fibular flap.

Osteonecrosis has long been recognized as a complication of systemic steroid use and was initially believed to occur only in patients who received high doses (equivalent to more than 4000 mg of prednisone) for extended periods (3 months or longer). Previous sporadic case reports have described patients in whom osteonecrosis developed following relatively brief courses (7 days) of lowdose, orall...

INTRODUCTION It has been well documented that labral tear is frequently associated with femoroacetabular impingement and dysplasia of the hip; however, there have been few reported cases of labral tear associated with idiopathic osteonecrosis of the hip. Here we report the case of a patient with labral tear associated with idiopathic osteonecrosis of the femoral head who was treated by hip arth...

OBJECTIVES The primary purpose of this meta-analysis was to determine whether statin usage could reduce the risk of glucocorticoid-related osteonecrosis in animal models. METHODS A systematic literature search up to May 2015 was carried out using the PubMed, Ovid, EBM reviews, ISI Web of Science, EBSCO, CBM, CNKI databases with the term and boolean operators: statins and osteonecrosis in all ...

The major cause of hip dislocations is motor vehicle collisions. A great deal of force is required to dislocate a hip, and thus associated injuries are common. Up to 88% of hip dislocations will be accompanied by an associated fracture. Patients with hip dislocations have about a 25% risk for osteoarthritis and a 20% risk for avascular necrosis. In addition, sciatic nerve injuries occur in appr...

PURPOSE Slipped capital femoral epiphysis (SCFE) is one of the most common adolescent hip conditions. Unstable SCFE is characterized by sudden and severe hip pain with the inability to weight bear, even with crutches. Osteonecrosis of the femoral head is increased in patients with unstable SCFE. The aim of our study was to systematically review the literature that compares hip decompression to ...