The purpose of this study was to explore the application of near-infrared spectroscopy (NIRS) to the assessment of peripheral arterial occlusive disease (PAOD). Muscle blood flow, oxygen consumption, arterial inflow capacity, O2 resaturation, and recovery times were determined at rest, under ischemic and hyperemic conditions, and continuously during and after walking exercise in 11 claudicants ...

The prefrontal cortex (PFC) plays an important role in cognitive function, involved in Executive Functions (EFs) such as planning, working memory, and inhibition. Activation in the PFC also occurs during some motor activities. One commonly used tool to assess EF is the Tower of Hanoi, demonstrating sensitivity to PFC dysfunction. However, limited neuroimaging evidence is available to support th...

Studies have shown that oxygenated compounds and TSS/TA are important for beverage and food industries. It seems that Citrus rootstocks have a profound influence on oxygenated compounds and TSS/TA. The aim of this research is to identify rootstock that can synthesize the maximum level of oxygenated compounds and TSS/TA. Peel oil was extracted using mechanical presses and eluted using n-hexane. ...

Static and dynamic deformabilities of erythrocytes are important determinants of microcirculatory blood flow. To determine the influence of increased cellular hemoglobin concentration on these properties, we quantitated static and dynamic deformabilities of isolated subpopulations of oxygenated normal and sickle erythrocytes with defined cell densities using micromechanical manipulations of ind...

Background and objectives: Homozygous sickle cell disease (SCD) patients frequently are alloimmunized resulting in restricted compatible blood supply. Methods to reduce exposure to allogeneic blood are not used frequently. Autologous blood from HbSS patients cannot be used because there is not a safe way to determine if it is suitable for re-transfusion.This feasibility study aims to establish ...

BACKGROUND Blood concentrations and oxygen saturation levels are important biomarkers for breast cancer diagnosis. OBJECTIVES In this study, the absorption coefficient of hemoglobin (Hb) was used to distinguish between normal and abnormal breast tissue. MATERIALS AND METHODS A near-infrared source (637 nm) was transmitted from major and minor vessels of a breast phantom containing 2×, 4× co...

Cerebral oximetry monitoring, used with the intention of optimizing perioperative outcomes, is increasingly being used in the setting of both cardiac and non-cardiac surgery. Cerebral oximetry had its early beginnings in the 1980s with the work of Jöbsis and colleagues. By using multi-wavelength light sources in the near infrared range, these early investigations demonstrated the potential util...

The protection of the ischemic neonatal myocardium was studied utilizing both cardioplegic and noncardioplegic solutions. Six groups of seven-day-old isolated working rabbit hearts, exposed to 120 minutes of hypothermic (3()oC) arrest, were treated with either an oxygenated or nonoxygenated cardioplegic or physiologic saline solution. The results indicated that postischemic aortic flow, stroke ...

Deoxygenation of alligator red blood cells (RBCs) caused binding of two [Formula: see text] equivalents per hemoglobin (Hb) tetramer at physiological pH. At lowered pH, some[Formula: see text] binding also occurred to oxygenated Hb. The erythrocytic total CO2 content was large, and Hb-bound [Formula: see text], free[Formula: see text], and carbamate contributed about equally in deoxygenated cel...