The Association for the Advancement of Medical Instrumentation (AAMI), a not-for-profit organization, writes standards for medical devices and is a country member of the International Organization for Standards (ISO). AAMI standards are reference guidelines for the United States Food and Drug Administration (FDA) and medical device manufacturers for the performance of all perfusion products’ su...

AGREAT variety of perfusion piunps and blood oxygenators have been described during the past 80 years. A review of the necessary qualifications for such devices is given in part by Bjork and by Dubbleman. During the past six years the author has designed, constructed and tested several heartlung machines. This report describes and discusses the one which as of 1952 showed the greatest possibili...

In order to facilitate the handling of cardiopulmonary bypass (CPB) and simplify the circuit, we have developed a new membrane oxyganator with a hemofiltration function. The hollow fiber units for gas exchange and hemofiltration were combined in concentric circles in a cylindrical housing. The total priming volume was 190 ml. Because we used a silicon-coated hollow fiber membrane for gas exchan...

BACKGROUND Anaesthetic requirements may be reduced following surgery employing cardiopulmonary bypass (CPB). This study, in dogs, determined the role of a) volatile agents (enflurane [E] vs isoflurane [I]), b) oxygenator (bubble [B] vs membrane [M]), and c) presence [FL] vs absence [NoFL] of an in-line arterial filter in the bypass circuit in altering anaesthetic requirements following CPB. M...

During a previously published study on gaseous microemboli (GMEs) and perfusionist interventions, it was noted that emboli could be detected after the arterial filter when blood/air challenges entered the membrane oxygenator's integral cardiotomy. The findings indicated that further study into the oxygenator's integral cardiotomy reservoir was warranted. This is the first know published report ...

Cytochalasin B, a fungal metabolite, has been shown to inhibit hexose transport in a variety of cellular types, including erythrocytes (Bloch, 1973), leucocytes (Zigmond & Hirsch, 1972), adipose-cell ‘ghosts’ (Czech et al., 1973), fibroblasts and liver cells (Kletzien et al., 1972) and HeLa cells (Mitzel & Wilson, 1972). Studies of effects of cytochalasin B on hexose transport in the nervous sy...

____________ _ Measurements of transcutaneous POz (tc POz), intraarterial P02(P;02) and P02 of blood samples taken from the sampling port of the oxygenator (PoOz) were compared with arterial blood P02 (PaOz) in 16 adult patients undergoing cardiopulmonary bypass. tcP02 and Pi02 were recorded continuously using Roche-Kontron electrodes. Po02 and PaOz were measured intermittently on a Radiometer ...