1. The native hormone-binding proteins, neurophysin-I and -II, have been isolated from acetone-desiccated bovine pituitary posterior lobes. 2. Neurophysin-I and -II are present in approximately equal quantities in the tissue and are localized in the neurosecretory granules. 3. The apparent molecular weight, determined by equilibrium sedimentation of neurophysin-I, was 19000 and that of neurophy...

OBJECTIVE To compare the effectiveness of sublingual misoprostol administered immediately after delivery of the neonate at cesarean section, with intravenous oxytocin infusion in prevention of uterine atony and thereby reducing blood loss at cesarean section. METHODS One hundred women with singleton term pregnancy undergoing elective or emergency lower segment cesarean section under spinal an...

Ending the silent pandemic of unsafe abortion is an urgent public-health and human-rights imperative. As with other more visible global-health issues, this scourge threatens women throughout the developing world. Every year, about 19-20 million abortions are done by individuals without the requisite skills, or in environments below minimum medical standards, or both. Nearly all unsafe abortions...

We report the successful treatment of a postpartum pyomyoma, a rare but serious complication of uterine leiomyomata in a 28-year-old primigravida. The patient was treated for an Escherichia Coli (E. Coli) urinary tract infection (UTI) at 16 weeks of gestation. She had asymptomatic short cervical length on ultrasound scan at 20 weeks that was managed conservatively due to the presence of further...

Over 80% of pregnant women in Western Uganda deliver at home with the assistance of mainly traditional birth attendants who use herbal remedies to complete the processes of child bearing in the rural communities. In Uganda, complications resulting from reproductive health related conditions such as maternal mortality and morbidity (20.4%) account for number one problem among the disease burden ...

To study the oxytocic effect of trypsin, we measured the force of isometric contraction in uteri isolated from estrogenized rats exposed to trypsin (8.8xl0~ to 1.7x10"' mol/L) either alone or in the presence of receptor antagonists to angiotensin II [saralasin ([Sar ,Ala]angiotensin II) or DuP 753 (losartan)] or to kinins (D-[Arg°,Hyp,Thi,D-Phe]bradykinin). We found that saralasin or DuP 753, b...

Marsupials have two anatomically separate uteri; and in macropodids (kangaroos and wallabies), there is a single ovulation from alternate ovaries in each cycle. During late pregnancy, the two uteri are differentially regulated by local hormonal influences from the corpus luteum, the fetus, and placenta on one side and by the developing Graafian follicle on the other. In this study, we report st...

The aim of the present study was to determine the uterotonic activities of Ficus asperifolia and investigate its mechanism. The effects of aqueous and methanol extracts of the dried fruits of F. asperifolia (0.05-1.60 mg mL(-1)) were evaluated on estrogenized isolated rat uterus in the presence and absence of atropine (1.73-55.27 nM), pyrilamine maleate (1.25 × 10(-3) to 40 × 10(-3) M), indomet...

Oshá or oshála is the traditional name of plants in the genera Lomatium and Ligusticum that are used medicinally by indigenous peoples in North and Central America. Oshá root has been used medicinally in women’s medicine as a natural contraceptive, an abortifacient, an emmenagogue, and an oxytocic agent. Given its traditional use in women’s medicine, previous researchers hypothesized that it wo...

1. Definitions ................................................................................... 2 1.1 Principles .......................................................................... 2 1.2 Australasian Definition ........................................................ 2 1.3 Diagnostic Challenge ........................................................ 4 2. Organisational Aspects ..........