Eight dinuclear Au(i)-carbene complexes have been synthesized from various imidazolium-linked cyclophanes and related acyclic bis(imidazolium) salts, by treatment of the imidazolium salts with [Au(i)(SMe(2))Cl] in the presence of a carboxylate base. Single crystal structural studies showed that the Au(i)-carbene compounds contain dinuclear (AuL)(2) cations in which a pair of gold(i) centres are...

We report for the first time steady-state and time-resolved emission properties of photosystem I (PSI) complexes isolated from the cyanobacterial strain Synechococcus WH 7803. The PSI complexes from this strain display an extremely small fluorescence emission yield at 77 K, which we attribute to the absence of so-called red antenna chlorophylls, chlorophylls with absorption maxima at wavelength...

In the present work the nature of lone-pair-π interactions between water molecules and a number of π-rings with different substituents/hetero-atoms in the light of quantum chemical topology approaches is studied. The Quantum Theory of Atoms in Molecules (QTAIM) and Interacting Quantum Atoms (IQA) were employed for distinguishing the role of heteroatoms and electron withdrawing substituents in t...

Breathing solitons are nonlinear waves in which the energy concentrates a localized and oscillatory fashion. Similarly to stationary solitons, breathers dissipative systems can form stable bound states displaying molecule-like dynamics, frequently called breather molecules. So far, experimental observation of optical molecules real-time detection their dynamics limited diatomic molecules, that ...

Obtaining quantities of highly pure duplex DNA is a bottleneck in the biophysical analysis of protein-DNA complexes. In traditional DNA purification methods, the individual cognate DNA strands are purified separately before annealing to form DNA duplexes. This approach works well for palindromic sequences, in which top and bottom strands are identical and duplex formation is typically complete....

The cellular functions of most RNA molecules involve protein binding, and non-Watson-Crick base pairs are hallmark sites for interactions with proteins. The determination of three-dimensional structures of RNA-peptide and RNA-protein complexes reveals the molecular basis of non-Watson-Crick base-pair recognition.

The KpnI sequences constitute the dominant, long, interspersed repetitive DNA families in primate genomes. These families contain related, but nonidentical sequence subsets, some of which border functional gene domains and are transcribed into RNA. To test whether these sequences perform an organizational function in the nucleus, their association with the nuclear matrix has been examined in Af...

INTRODUCTION Nimesulide is a relatively cyclo-oxygenase-2 (COX2) selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old to decrease the risk of hepatotoxicity. It may be used orall...

Binuclear diaminocarbene complexes, which form as a regioisomer mixture in the reaction between isocyanide–palladium(II) complex cis-[PdCl2(CNXyl)2] and 1,3-thiazol-2-amine, are able to exchange an anionic chloride ligand with other halides, such Br or I. This process also affords binuclear complexes mixtures of kinetically thermodynamically controlled regioisomers. In CDCl3 solutions, we obser...

Hybrid functional calculations are presented for defects in LiGaO2 with the fraction of non-local exchange adjusted to reproduce recently reported exciton gap 6.0 eV. We study how defect transition levels main native change respect band edges compared earlier which assumed a smaller bandgap near 5.1 In addition, we consider complexes formed by combining donor GaLi acceptors, VLi and LiGa antisi...