نتایج جستجو برای: panel reactive antibody

تعداد نتایج: 396266  

2002
David Brown Mick Howes Karim Hussein Catherine Longley Ken Swindell

This research examines the conduct and consequences of the use of participatory rural appraisal techniques in four rural development projects in The Gambia. The research included a review of literature on PRA and the identification of a series of key themes that would allow an assessment of its utility. Fieldwork in The Gambia included reviews of project documentation, key informant interviews,...

Journal: :Transplantation 1990
J L Holley R Shapiro W B Lopatin A G Tzakis T R Hakala T E Starzl

Obesity has generally been thought to increase the risk of operative mortality and postoperative complications in surgical patients. No data examining obesity as a factor in cadaveric renal transplantation were available. We therefore matched obese patients undergoing cadaveric renal transplantation with nonobese control patients and retrospectively analyzed mortality, morbidity, and graft surv...

Journal: :Transplantation 2016
Barry I Freedman Stephen O Pastan Ajay K Israni David Schladt Bruce A Julian Michael D Gautreaux Vera Hauptfeld Robert A Bray Howard M Gebel Allan D Kirk Robert S Gaston Jeffrey Rogers Alan C Farney Giuseppe Orlando Robert J Stratta Sumit Mohan Lijun Ma Carl D Langefeld Donald W Bowden Pamela J Hicks Nicholette D Palmer Amudha Palanisamy Amber M Reeves-Daniel W Mark Brown Jasmin Divers

BACKGROUND Two apolipoprotein L1 gene (APOL1) renal-risk variants in donors and African American (AA) recipient race are associated with worse allograft survival in deceased-donor kidney transplantation (DDKT) from AA donors. To detect other factors impacting allograft survival from deceased AA kidney donors, APOL1 renal-risk variants were genotyped in additional AA kidney donors. METHODS The...

2017
Melanie King Rosario Shahirose Sadrudin Premji Elias Charles Nyanza Shelley Raffin Bouchal David Este

OBJECTIVES To explore and understand the experiences and priorities of pregnant women living with fears and worries related to fetal/infant and maternal health, the birthing process and ability to parent the infant (ie, pregnancy-related anxiety (PRA)) in Mwanza, Tanzania. DESIGN Descriptive phenomenological approach. SETTING Two clinics in the Ilemela and Nyamagana districts of Mwanza. P...

Journal: :BMC Infectious Diseases 2001
Robert T Sarisky H Ron Bartus Shelley A Dennis Matthew R Quail Tammy T Nguyen Robert J Wittrock Wendy S Halsey Teresa H Bacon Jeffry J Leary David Sutton

BACKGROUND Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of resistance following suboptimal treatment with valacyclovir (VCV) or famciclovir (FCV), the prodrugs of acyclovir and penciclovir, respectively, have been reported. METHODS Mice (n = 3...

Journal: :Clinical journal of the American Society of Nephrology : CJASN 2012
James R Cassuto Matthew H Levine Peter P Reese Roy D Bloom Simin Goral Ali Naji Peter L Abt

BACKGROUND AND OBJECTIVES Non-renal transplant recipients who subsequently develop ESRD and undergo kidney transplantation are medically and immunologically complex due to comorbidities, high cumulative exposure to immunosuppressants, and sensitization to alloantigen from the prior transplant. Although prior non-renal transplant recipients are one of the fastest growing segments of the kidney w...

Journal: :Pediatrics 2014
Kyle J Van Arendonk Brian J Boyarsky Babak J Orandi Nathan T James Jodi M Smith Paul M Colombani Dorry L Segev

OBJECTIVE To investigate changes in pediatric kidney transplant outcomes over time and potential variations in these changes between the early and late posttransplant periods and across subgroups based on recipient, donor, and transplant characteristics. METHODS Using multiple logistic regression and multivariable Cox models, graft and patient outcomes were analyzed in 17,446 pediatric kidney...

2017
Rosa Maria Vivanco‐Hidalgo Alejandra Gomez Antia Moreira Laura Díez Roberto Elosua Jaume Roquer

OBJECTIVES Epilepsy has been associated with cardiovascular comorbidity. This study aimed to assess the potential association between cardiovascular risk factors (CRFs), antiepileptic drugs (AEDs), and etiology. MATERIAL AND METHODS A single-center retrospective epilepsy cohort from the decade of 2004-2013 was assessed. Poisson regression models with robust variance were estimated to obtain C...

Journal: :Transplantation proceedings 1999
R Shapiro M L Jordan V P Scantlebury C Vivas J W Marsh J McCauley J Johnston P Randhawa W Irish H A Gritsch R Naraghi T R Hakala J J Fung T E Starzl

BETWEEN September 10, 1995, and September 20, 1997, a total of 208 adult patients undergoing their first or second cadaveric renal transplantation alone were randomized to receive tacrolimus!prednisone (n = 106) or tacrolimus/prednisone/mycophenolate mofetil (n = 102), without induction antilymphocyte antibody therapy. The mean recipient age was 50.8 ::!:: 13.7 years (range 19 to 84). Thirty-on...

2003
THOMAS E. CREIGHTON

Yanofsky (1) originally proposed N-(5’-phosphoribosyl)anthranilic acid as the first intermediate after anthranilic acid in tryptophan biosynthesis in microorganisms. Evidence was subsequently found which suggested that this compound is formed enzymatically from anthranilic acid and ribosylpyrophosphate 5-phosphate (2, 3). Although the dephosphorylated form of PRA,’ N-ribosylanthranilic acid, ha...

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