Panton–Valentine leukocidin (PVL) is among one of the many toxins associated with Staphylococcus aureus infection. It commonly causes recurrent skin and soft tissue infections (SSTIs), but can sometimes be severe invasive infections, including necrotising haemorrhagic pneumonia in otherwise healthy young people. Here we report a case male patient who presented community acquired that very rapid...

The Lighthill–Panton and Lyman–Huggins interpretations of vorticity dynamics are extended to the enstrophy. There exist two competing definitions current tensor, which describes flow rate in fluid interior, corresponding boundary flux, represents local creation on a boundary. It is demonstrated that each definition tensor leads consistent set for enstrophy current, flux dissipation term. This a...

The history of Panton Valentine leucocidin (PVL), one of the toxins of Staphylococcus aureus, began in 1894, 24 years after Sir Alexander Ogston and Louis Pasteur had reproduced human pyemic infections in mice and rabbits by inoculating pus or pus-derived cultures (11,14). The torch of PVL research was then handed down over the decades between small groups of scientists fascinated by S. aureus ...

The Staphylococcus aureus Panton-Valentine leukocidin (PVL) is a pore-forming toxin secreted by strains epidemiologically associated with the current outbreak of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and with the often-lethal necrotizing pneumonia. To investigate the role of PVL in pulmonary disease, we tested the pathogenicity of clinical isolates, isogenic...

A total of 19 methicillin-resistant Staphylococcus aureus (MRSA) isolates were investigated for Panton-Valentine leukocidin (PVL) toxin, PVL gene sequence variation and PVL-encoding phages. Whole genome sequencing was performed for all isolates. Analysis of MRSA isolates (n = 19) confirmed that most MRSA (n = 11) were positive for the PVL gene and were multidrug resistant. ST772-MRSA-V was the ...

Staphylococcus aureus is a common cause of musculoskeletal infections. Panton-Valentine leukocidin (PVL) is an exotoxin produced by S. aureus and is an important virulence factor. PVL-positive S. aureus infections have been associated with soft tissue infections and necrotizing pneumonia. In this case report, the clinical course of a 13-year-old boy who was admitted with right hip pain and feve...

We report the identification and characterization of three Staphylococcus aureus isolates recovered from throat and vaginal cultures, as well as from an axillary abscess, of a 17-year-old female who died of tampon-related toxic shock syndrome. The three S. aureus isolates were unrelated as determined by pulsed-field gel electrophoresis. The vaginal isolate was mecA, Panton-Valentine leukocidin,...