OBJECTIVE To examine whether in smokers there is a significant dose dependency between the number of cigarettes per day and levels of free ss-hCG and pregnancy-associated plasma protein A (PAPP-A) at 11-13(+6) weeks of gestation. METHODS This was a retrospective analysis of the maternal serum free ss-hCG and PAPP-A levels in relation to the maternal smoking status in 109 263 chromosomally nor...

Although IGFs are indispensable to skeletal muscle development, little information is available regarding the mechanisms regulating the local action of IGFs in skeletal muscle tissues. Here we tested the hypothesis that pregnancy-associated plasma protein-A (PAPP-A), a member of the metalloproteinase superfamily, promotes skeletal muscle formation in vivo through degrading IGF binding proteins ...

BACKGROUND Early diagnosis is the cornerstone of management of acute myocardial infarction (AMI). We aimed to compare the diagnostic accuracy of high-sensitivity troponin T (hs-cTnT) with myeloperoxidase (MPO) and pregnancy-associated plasma protein A (PAPP-A) for early diagnosis of AMI in patients at the time of presentation to the emergency department (ED). METHODS We enrolled 289 patients ...

OBJECTIVES To examine the clinical utility of the first-trimester markers of aneuploidy in their ability to predict future fetal loss. METHODS We examined 54,722 singleton pregnancies with no chromosomal abnormality and with complete outcome data that had undergone screening for trisomy 21 by a combination of fetal nuchal translucency (NT) thickness, maternal serum free beta-human chorionic g...

BACKGROUND/AIM Pregnancy-associated plasma protein A (PAPP-A) is high molecular matrix metalloproteinase originally isolated in the serum of pregnant women. The aim of this study was to analyze the values of concentration of PAPP-A in assessment of progress and outcome of pregnancy in pregnant women diagnosed with threatening preterm delivery, preeclampsia and fetal growth restriction in relati...

Introduction/Objective. Fetal growth restriction (FGR) is associated with increased fetal and neonatal mortality morbidity. The study objective was to investigate the correlation of maternal blood biochemical markers routinely determined in first second trimester screening ultrasound surveillance parameters prediction condition singleton pregnancies. Methods. In we measured serum levels beta su...

Two new species of the genus Cratospila Foerster, 1863 (Braconidae: Alysiinae), albosignata sp. nov. and C. longivena , are described illustrated. In addition, DNA barcode region mitochondrial cytochrome c oxidase subunit I ( COI ) both has been sequenced with three previously albifera luteocephala syntoma ). Alysia ponerola Papp, 2009 which was recorded from North Korea is transfered in (Papp,...