Dynamic changes in synaptic connectivity and strength, which occur during both embryonic development and learning, have the tendency to destabilize neural circuits. To overcome this, neurons have developed a diversity of homeostatic mechanisms to maintain firing within physiologically defined limits. In this study, we show that activity-dependent control of mRNA for a specific voltage-gated Na+...

Neste trabalho é proposto um método espectrofotométrico modificado para a determinação de diclofenaco em preparações farmacêuticas. Usa-se solução de cobre(II) como reagente, o que leva à formação de um complexo cobre(II)-diclofenaco de cor verde, com máximo de absorção em 680 nm. Foram estudadas as influências: do pH; da concentração de cobre(II); do uso de ácido acético na solução de cobre(II...

This article presents DialogBuilder, an open-source Java tool that provides to its user an interface for designing dialog systems and exporting them to code that can be deployed in Asterisk, the most popular VoIP framework. DialogBuilder offers to the novice users a wizard so that they can design their own dialog system without learning the intricacies of programming for Asterisk. The software ...

Three large negatively charged organic host molecules; β-cyclodextrin sulphate, para-sulphonato-calix[6]arene and para-sulphonato-calix[8]arene have been shown to be effective inhibitors of endonuclease in the low micromolar range, additionally para-sulphonato-calix[8]arene is a partial inhibitor of rhDNase I.

5,8-Didehydroisoquinolinium ion, a para benzyne analogue, was generated in a Fourier transform ion cyclotron resonance mass spectrometer, and its reactivity toward various neutral reagents was examined. A direct comparison of the reaction kinetics of the para benzyne, a meta isomer, and analogous monoradicals, indicates that the para benzyne is a poorer electrophile but a more reactive radical ...

We give an elementary proof of the fact that any 4-dimensional para-Hermitian manifold admits a unique para-Kähler–Weyl structure. We then use analytic continuation to pass from the para-complex to the complex setting and thereby show that any 4-dimensional pseudo-Hermitian manifold also admits a unique Kähler–Weyl structure.