A 52-year-old woman, a hemodialysis patient, was admitted because of exertional dyspnea. Echocardiography showed left ventricular (LV) dilatation and reduced contraction. Coronary angiography showed no fixed stenosis. She had elevated levels of parathyroid hormone (PTH) as a result of secondary hyperparathyroidism with advanced renal failure. After parathyroidectomy, marked improvement of LV fu...

Two patients with long-standing hyperparathyroidism due to a parathyroid adenoma are described. Both had severe osteitis fibrosa cystica and a proximal myopathy. Both were treated with alfacalcidol (2 micrograms/day) prior to and following parathyroidectomy, and infused with calcium gluconate following the operation. Plasma total and ionized calcium and magnesium concentrations were maintained ...

After nearly a century of performing thyroidectomy essentially the way it was described by Theodore Kocher in the nineteenth century, the technique has quickly evolved. Parathyroidectomy has advanced as biochemical assays and physiologic imaging have become available. Minimally invasive and endoscopic thyroidectomy and parathyroidectomy can now be performed in many patients who benefit from the...

Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient population. This condition is usually the result of a single hyperfunctioning parathyroid gland. Targeted parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IPM) through a small cervical incision has replaced traditional bilateral neck exploration (BNE) as the initial approach in the ...

In this retrospective study of 57 patients with primary hyperparathyroidism who underwent parathyroidectomy, the overall incidence of chondrocalcinosis was 40%. Neither joint symptoms nor chondrocalcinosis regressed after the operation. In several patients the condition appeared to deteriorate both clinically and radiologically after the operation, while in a few both the chondrocalcinosis and ...

background: calciphylaxis is a serious disorder often observed in dialysis patients and less frequently in chronic renal failure patients with secondary hyperparathyroidism. mortality rate increases following the development of calciphylaxis, immediate application of parathyroidectomy along with other treatment options may be lifesaving. case presentation: a 44-year-old male patient had been on...

Renal anemia and chronic kidney disease-mineral bone disorder (CKD-MBD) are common in patients with disease (CKD). Blood metabolic biomarkers non-invasive indexes for evaluating renal osteodystrophy. Here the relationships between blood CKD investigated, effects of parathyroidectomy (PTX) on above indices analyzed.

The existing body of evidence suggests that cinacalcet is an effective drug for secondary hyperparathyroidism (SHPT) control in patients undergoing maintenance dialysis (CKD-5D) [1–10]. Indeed, available evidence suggests that by modulating the parathyroid calcium-sensing receptor affinity to serum calcium, cinacalcet lowers by 40–50% (250–350 pg/mL) serum parathyroid hormone (PTH) (Table 1). A...