PURPOSE To better characterize the cellular constituents of cysts in the peripheral retina and pars plana of the adult monkey. METHODS Frozen sections of the peripheral retinal margin and pars plana from monkeys (Macaca nemestrina) between 1 and 15 years of age were stained with toluidine blue or immunolabeled with a variety of glia- and neuron-specific antibodies. RESULTS In animals 1 to 2...

The economic production and the interactive rendering of complete reconstructions of populated urban environments are technically difficult tasks. Specialized modelling tools, which exploit knowledge of the types of object being modelled by working in the application domain, can be used to create appealing virtual reconstructions quickly. At the same time, the structural information from the mo...

Evaluation and validation of homology modeling protocols are indispensable for membrane proteins as experimental determination of their three-dimensional structure is an arduous task. The prediction ability of Modeller, MOE, InsightII-Homology and Swiss-PdbViewer (SPV) with different sequence alignments CLUSTALW, BLAST and 3D-JIGSAW have been assessed. The sequence identity of the target and te...

In this paper, we present a set of Eclipse plug-ins which adapts the idea of regression testing for the area of visual modelling in software engineering: Expected properties of models in languages such as UML, BPMN, etc. are stored together with the model (comparable with test cases added to software). With each change of the model, these properties can be checked. The solution should work with...

Protease-activated receptors (PARs) belong to the superfamily of seven transmembrane domain G protein-coupled receptors. Four PAR subtypes are known, PAR-1 to -4. PARs are highly homologous between the species and are expressed in a wide variety of tissues and cell types. Of particular interest is the role which these receptors play in the brain, with regard to neuroprotection or degeneration u...

The ultrastructures of the pituitary pars intermedia of 11 male sheep about 1-13 months of age were observed. The following cells were distinguished in the sheep pars intermedia: pars intermedia glandular cells, marginal cells, interstitial cells, follicular cells, pars distalis-like granular cells, degenerating cells and mast cells. The pars intermedia glandular cells contain a well-developed ...

Evidence from electrophysiological studies has suggested an inhibitory interaction between GABAergic neurons in substantia nigra pars reticulata and dopaminergic neurons in pars compacta. However, that this inhibitory interaction is due to a projection from pars reticulata to pars compacta has never been demonstrated directly, nor has the GABAergic neuron that mediates the interaction been iden...

The pars opercularis occupies the posterior part of the inferior frontal gyrus. Electrical stimulation or damage of this region interferes with language production. The present study investigated the morphology and morphometry of the pars opercularis in 108 normal adult human cerebral hemispheres by means of magnetic resonance imaging. The brain images were transformed into a standardized propo...

Poly(ADP-ribose) synthetase (PARS) activation: a pathway of cellular oxidant injury PARS is a protein-modifying and nucleotidepolymerizing enzyme that is abundantly present in the nucleus [l]. Its activation results in the cleavage of NAD' into ADP-ribose and nicotinamide. In turn, PARS covalently attaches ADPribose to various proteins, including nuclear proteins, histones and an automodificati...