the aim of the present study was to develop exemestane loaded polymeric nanoparticles for improved oral bioavailability of exemestane. exemestane loaded nanoparticles were prepared by solvent displacement method with eudragit rl 100 and eudragit l 100 as polymers and pluronic® f-68 as surfactant. the influence of various formulation factors (drug: polymer ratio and concentration of surfactant) ...

The objective of this experiment was to evaluate effects of reducing forage particle size on cows in early lactation based on measurements of the Penn State Particle Separator (PSPS). Eight cannulated, multiparous cows averaging 19 +/- 4 d in milk and 642 +/- 45 kg BW were assigned to one of two 4 x 4 Latin Squares. During each of the 23-d periods, animals were offered one of four diets, which ...

background and aims. adding further fillers to dental resins may enhance their physical characteristics. the aim of this study was to evaluate the tensile strength of heat-curing acrylic resin reinforced by tio2 nanoparticles added into the resin matrix. materials and methods. commercially available tio2 nanoparticles were obtained and characterized using x-ray diffraction (xrd) and scanning ele...

Effects of particle size and physical effective fibre (peNDF) of rice straw in diets on chewing activities, feed intake, flow, site and extent of digestion and rumen fermentation in goats were investigated. A 4×4 Latin square design was employed using 4 mature Liuyang black goats fitted with permanent ruminal, duodenal, and terminal ileal fistulae. During each of the 4 periods, goats were offer...

Two experiments were conducted to determine effects of particle size in total mixed ration (TMR) on performance of lactating cows. Three rumen cannulated Holstein cows were used in a 3×3 Latin square design for the metabolic experiment. The particle size of the diets was determined using the Penn State Particle Size Separator (PSPSS) and weighing the proportion of sample remaining on the top sc...