Exposure to heavy metals is the most important risk factor in the assessment of spermatogenesis. About 30-40 % cases of infertility are caused by the male factor, and most of them are due to the small quantity of spermatozoa or to inferior spermatozoa quality. The negative impact on sperm motility, morphology and concentration of such ...

Xenobiotic-metabolizing cytochrome P-450 (P-450) enzymes not only play a pivotal role in elimination of foreign compounds but also contribute to generation of toxic intermediates, including reactive oxygen species, that may elicit cellular damage if produced excessively. Expression of several xenobiotic-metabolizing P-450 enzymes is induced by phenobarbital (PB). Pronounced induction is observe...

This study aimed at evaluating the effects of trailer design on stress responses and meat quality traits of 3 different pig crosses: 50% Pietrain breeding with halothane (HAL)(Nn) (50Nn); 50% Pietrain breeding with HAL(NN) (50NN); and 25% Pietrain breeding with HAL(NN) genotype (25NN). Over a 6-wk period, pigs (120 pigs/crossbreed) were transported for 7 h in either a pot-belly (PB) or flat-dec...

the toxicity of four potentially toxic trace elements (cu, ni, pb and zn) to annual atriplex (a.hortensis and a. rosea) was examined to determine if this plant showed sufficient tolerance to be used tophytoremediate soils polluted with these heavy metals. the soils, which contained up to (per kilogram) 501mg cu, 1674 mg ni, 1334 mg pb and 3588 mg of zn were sampled around metal-contaminated sit...

In this study, the influence of lead (II) ions on sunflower growth and biochemistry was investigated from various points of view. Sunflower plants were treated with 0, 10, 50, 100 and/or 500 μM Pb-EDTA for eight days. We observed alterations in growth in all experimental groups compared with non-treated control plants. Further we determined total content of proteins by a Bradford protein assay....

The erythrocytes deliver oxygen to all around body cells that make them extremely vital for the metabolism. Metals are transferred through the blood, meaning the erythrocytes face with metals continuously. The present study intended to explore the responses of osmoregulation (Na/K-ATPase, Mg-ATPase, Ca-ATPase) and antioxidant system parameters (CAT, SOD, GPX, GR, GST, tGSH, rGSH, GSSG, GSH/GSSG...

PURPOSE To study the effect of Cleistocalyx nervosum extract (CE) on diethylnitrosamine (DEN) and phenobarbital (PB) induced oxidative stress in early stages of rat hepatocarcinogenesis. MATERIALS AND METHODS Male Wistar rats were divided into 4 groups, with Group 1 as a negative control and Group 2 was a positive control receiving DEN injections once a week and PB in drinking water for 6 wee...

The aim of this study was to compare the tolerance of seedlings of three Polish buckwheat cultivars (Hruszowska, Kora, and Luba) for short-term exposure to Pb and Cd. Seedlings were grown under controlled conditions in Hoagland nutrient solution, with the addition of low/high Pb or Cd ions (0.01 and 1.00 mM, respectively). After 3 days of treated seedling growth, the levels of total anthocyanin...

The vibration fatigue durability of eutectic Sn37Pb and near-eutectic Pb-free Sn3.9Ag0.6Cu solders is quantified, based on test data available from the literature [1]. The tests use random broad-band excitation (between 20Hz & 2000Hz), on selected SAC and SnPb surface mount interconnect styles. In the test, step-stress excitation was applied in the out-of-plane direction by increasing the RMS e...

The c-Jun N-terminal kinase (JNK) is part of a mitogen-activated protein kinase (MAPK) signaling cascade. Scaffold proteins simultaneously associate with various components of the MAPK signaling pathway and play a role in signal transmission and regulation. Here we describe the identification of a novel scaffold JNK-binding protein, WDR62, with no sequence homology to any of the known scaffold ...