BACKGROUND Persistent pollutants, such as polychlorinated biphenyls (PCBs), affect endocrine function. Human exposure to polybrominated diphenyl ethers (PBDEs), which are similar in structure to PCBs, has increased recently, but health effects have not been well studied. OBJECTIVES Our goal in this study was to determine whether PBDE body burdens are related to thyroid and steroid hormone lev...

Since polybrominated diphenyl ether (PBDE) flame retardants were withdrawn from use in polyurethane foam padding, alternatives including tris(1,3-dichloropropyl) phosphate (TDCIPP) and triphenyl phosphate (TPHP) are now used in consumer goods including furniture, automobiles, carpet padding, and baby products. Like PBDEs, these replacement compounds have been widely found in dust samples from h...

Using Raman spectroscopy without any preparation, we analyzed the brominated flame retardant, polybromodiphenyl ethers (PBDEs), which has been prohibited by the European Union. The typical Raman bands of PBDEs, which are clearly different from those of other brominated flame retardants, are from 100 to 300 cm(-1). In our analysis, the detection limit was about 100 ppm, and the analysis took abo...

Polybrominated diphenyl ethers (PBDEs) are brominated flame retardants (BFRs) which have routinely been added to consumer products for several decades in a successful effort to reduce fire-related injury and property damage. Recently, concern for this emerging class of chemicals has risen because of their occurrence and observed increasing temporal trends in the environment and in human biota. ...

Data on early human fetal exposure to polybrominated diphenyl ethers (PBDEs) is limited. However, early pregnancy, in particular the first trimester, is critical for fetal development. We investigated exposure to PBDEs and placental transfer during early pregnancy by analyzing PBDEs in paired aborted fetuses (n = 65), placentas (n = 65), and maternal blood samples (n = 31) at 10-13 weeks gestat...

Areas containing industrial facilities belonging to three different typical industries that may cause pollution by polybrominated diphenyl ethers (PBDEs) in Beijing, China were investigated. Specifically, the areas contained a solid waste incineration plant, a chemical factory, and a heat and power plant. Investigation of the pollution status of PBDEs in the surface soil from areas around these...

Introduction: Polybrominated diphenyl ethers (PBDEs) have been used as flame retardants for several decades in the United States. Their incorporation into mattress coverings, carpeting, upholstery fabric, clothing and plastics have greatly reduced fire-related deaths. However, their widespread use and resistance to degradation have resulted in global contamination. PBDEs have a tendency to bioa...

We have measured the levels of flame retardants, polybrominated diphenyl ethers (PBDEs), in 20 recent human adipose tissues from Belgium and compared them to other organohalogen compounds such as polychlorinated biphenyls (PCBs), hexachlorobenzene, 2,2-bis(4-chlorophenyl)-1,1,1-trichloroethane (p,p'-DDT), and its metabolite, 2,2-bis(4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE). After Soxhlet...

OBJECTIVE Our aim was to investigate exposure to polybrominated diphenyl ethers (PBDEs) in a young urban population in a developing country, with focus on potentially highly exposed children working informally as scrap scavengers at a large municipal waste disposal site. We also set out to investigate whether hydroxylated metabolites, which not hitherto have been found retained in humans, could...

Polybrominated diphenyl ethers (PBDEs) and polybrominated bipyrroles are natural products that bioaccumulate in the marine food chain. PBDEs have attracted widespread attention because of their persistence in the environment and potential toxicity to humans. However, the natural origins of PBDE biosynthesis are not known. Here we report marine bacteria as producers of PBDEs and establish a gene...