نتایج جستجو برای: pbe
تعداد نتایج: 902 فیلتر نتایج به سال:
UNLABELLED Use of opioid analgesics for pain management has increased dramatically over the past decade, with corresponding increases in negative sequelae including overdose and death. There is currently no well-validated objective means of accurately identifying patients likely to experience good analgesia with low side effects and abuse risk prior to initiating opioid therapy. This paper disc...
The objective of the present paper is to develop a population balance approach for modelling soot formation that distinguishes between coalescence and aggregation accounts finite-rate fusing primary particles within aggregates, while providing numerically accurate description particle surface growth oxidation aggregates. To this end, recently developed conservative finite volume sectional metho...
The size at which nonplanar isomers of neutral, pristine gold nanoclusters become energetically favored over planar ones is still debated amongst theoreticians and experimentalists. Spectroscopy confirms planarity is preferred at sizes up to Au7, however, starting with Au8, the uncertainty remains for larger nanoclusters. Au8 computational studies have had different outcomes: the planar D4h "cl...
We evaluated the levels of mRNAs encoding cationic proteins in peripheral blood eosinophils (PBE) purified from patients with eosinophilia and in eosinophils differentiated from cord blood cells (CBC) by culture with recombinant human interleukin-3 (rhIL-3), rhGM-CSF, and rhIL-5. Messenger RNAs encoding eosinophil peroxidase (EPO), major basic protein (MBP), eosinophil-derived neurotoxin (EDN),...
Knowledge about the electrostatic potential on the surface of biomolecules or biomembranes under physiological conditions is an important step in the attempt to characterize the physico-chemical properties of these molecules and, in particular, also their interactions with each other. Additionally, knowledge about solution electrostatics may also guide the design of molecules with specified pro...
(PBE), is a complex mixture of bioflavonoids with oligomeric proanthocyanidin as main constituents. The nutritional supplementation of PBE produces a variety of potentially protective effects against chronic age-related diseases such as atherosclerosis, hypertension, and diabetes. It has recently been reported that many beneficial effects of PBE are closely related to its potent antioxidative a...
Programming-by-example (PBE) systems attempt to generate programs by learning a task from the user’s actions. It is a field with great potential, but little success so far. Most existing PBE systems are both highly specialised and quite limited in the tasks they can accomplish. This paper sets out a new approach to PBE that is general-purpose and can handle variables, branching and loops. It co...
Binding energy curves have been calculated for the ground-state rare-gas diatomics Ne(2) and Ar(2) and for the alkaline-earth diatomic Be(2) using the nonempirical density functionals from the first three rungs of a ladder of approximations: the local spin density (LSD) approximation, the Perdew-Burke-Ernzerhof (PBE) generalized gradient approximation (GGA), and the Tao-Perdew-Staroverov-Scuser...
Specific metabolic pathways are activated by different nutrients to adapt the organism to available resources. Although essential, these mechanisms are incompletely defined. Here, we report that medium-chain fatty acids contained in coconut oil, a major source of dietary fat, induce the liver ω-oxidation genes Cyp4a10 and Cyp4a14 to increase the production of dicarboxylic fatty acids. Furthermo...
We study a model of decentralised bilateral interactions in a small market where one of the sellers has private information about her value. There are two identical buyers and another seller, apart from the informed one, whose valuation is commonly known to be in between the two possible valuations of the informed seller. This represents an attempt to model alternatives to current partners on b...
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