OBJECTIVES The aim of this study is to modify and validate a novel screening tool to determine the necessity of bone scans in Chinese PCa patients at the time of diagnosis. METHODS Five-hundred-and-one patients diagnosed with PCa between 2010 and 2013 at Zhongshan Hospital, Fudan University, were included in the study. All received bone scans using technetium 99m methylene diphosphonate (99mT...

BACKGROUND Hip fractures are associated with increased mortality and are a known adverse effect of androgen deprivation therapy (ADT) for prostate cancer (PCa). It was our aim to evaluate how mortality after hip fracture is modified by PCa and ADT. METHODS PCa dataBase Sweden (PCBaSe 2.0) is based on the National PCa Register and also contains age and county-matched PCa-free men. We selected ...

BACKGROUND Coronary artery disease (CAD) and prostate cancer (PCa) are not only common diseases, but share many risk factors. To date, only a few studies have explored the relationship between CAD and PCa risk, with conflicting results. METHODS The four-year REDUCE study tested dutasteride 0.5 mg daily for PCa risk reduction in men with prostate specific antigen (PSA) of 2.5 to 10.0 ng/mL and...

acoustic analysis is a proper method in vocal fold pathology diagnosis so that itcan complement and in some cases replace the other invasive, based on direct vocalfold observation, methods. there are different approaches and algorithms for vocalfold pathology diagnosis. these algorithms usually have three stages which arefeature extraction, feature reduction and classification. in this paper in...

Although estrogen receptor beta (ERβ) has been implicated in prostate cancer (PCa) progression, its potential role in health disparity of PCa remains elusive. The objective of this study was to examine serum estrogens and prostate tumor ERβ expression and examine their correlation with clinical and pathological parameters in African American (AA) versus Caucasian American (CA) men. The circulat...

The acoustic data remotely measured by microphones are widely used to investigate monitoring and diagnose integrity of ball bearing in rotational machines. Early fault diagnosis is very difficult for acoustic emission. We propose a new method using a cross-correlation of frequency spectrum to classify various faults with fine grit. Principal component analysis (PCA) is used to separate the prim...

In this paper, it is proposed to develop the fault diagnosis system using the principal component analysis (PCA) for the intelligent operation support system that calculates the effect of fault propagation in abnormalities situation and gives appropriate information to plant operators. This proposed system using PCA discriminates a failure of equipment based on process variables. The proposed m...

BACKGROUND AND PURPOSE At diagnosis, the primary clinical manifestations of pediatric Moyamoya disease are TIA or CSs. CSs are reported to be more prevalent in younger than in older children. We sought to determine whether age-related differences in clinical manifestations are associated with age-related angiographic differences. MATERIALS AND METHODS We divided 78 patients diagnosed with Moy...

AIM OF THE STUDY Gleason score stratification according to age at diagnosis has been retrospectively evaluated in 1028 men with biopsy-proven prostate cancer (PCa). MATERIAL AND METHODS From January 2006 to December 2014, 2435 Caucasian men aged between 37 and 92 years underwent transperineal prostate biopsy for suspicion of PCa. The indications were as follows: abnormal digital rectal examin...

Prostate cancer (PCa) research in China has been on a rocketing trend in recent years. The first genome-wide association study (GWAS) in China identified two new PCa risk associated single nucleotide polymorphisms (SNPs). Next generation sequencing is beginning to be used, yielding novel findings: gene fusions, long non-coding RNAs and other variations. Mechanisms of PCa progression have been i...