Genetic groups, also called unknown or phantom parents are often used in dairy cattle genetic evaluations to account for selection that cannot be accounted by known relationships. With the advent of genomic evaluations, theory groups was extended so-called single-step BLUP (ssGBLUP). In short, can fitted ssGBLUP through regression effects, including them pedigree and computing adequate combined...

Chromosome 22q has become recently a region of interest for prostate cancer. We identified previously a logarithm of odds (LOD) of 2.42 at chromosome 22q12.3. Additionally, this region has been noted by eight other studies, with linkage evidence ranging from LOD of 1.50 to 3.57. Here, we do fine mapping and localization of the region using a pedigree-specific recombinant mapping approach in 14 ...

Estimates of effective population size in the Holstein cattle breed have usually been low despite the large number of animals that constitute this breed. Effective population size is inversely related to the rates at which coancestry and inbreeding increase and these rates have been high as a consequence of intense and accurate selection. Traditionally, coancestry and inbreeding coefficients ha...

The aim of the research is to study probability manifestation haplotype fertility AH1 in Ayrshire sires with different variants presence AH1C male ancestors first four rows their pedigree. Materials and methods. material was data electronic database created at RRIFAGB on 74 sire breed Russia, which 22 are carriers genetic defect - AH1C, rest free AH1F. To find patterns tested bulls, we analyzed...

DATA QUALITY AND PEDIGREE Introduction Data are scientific or technical measurements represented by numbers or other means [1]. Their importance in scientific and engineering work can never be stressed enough. The heart and soul of statistical analysis are the data. It is well known that bad data induces the so-called GIGO model: Garbage In, Garbage Out. In plain English, no statistical procedu...

During the past two decades, pedigree analysis has documented inbreeding depression in many captive populations. This and subsequent research has led to a recognition that inbreeding depression is a potentially important determinate of small population fitness, in both captivity and the wild. Modern captive-breeding programmes now universally avoid inbreeding. We use simulation to investigate h...

BACKGROUND Familial hypertrophic cardiomyopathy is the most common inherited cardiac disorder, with sudden cardiac death at a young age the most frequent cause of death in affected individuals. Some cases of familial hypertrophic cardiomyopathy are caused by missense mutations of the beta myosin heavy chain (beta MHC) gene on chromosome 14 and at least 17 such mutations have been described. Rec...