نتایج جستجو برای: peginterferon alfa
تعداد نتایج: 19203 فیلتر نتایج به سال:
BACKGROUND Peginterferon alfa and ribavirin combination therapy is an effective treatment for many patients with chronic hepatitis C virus (HCV). Reducing the length of treatment may be advantageous. We performed a systematic review and economic evaluation to assess shorter treatment duration of this regimen. METHODS We searched fourteen bibliographic databases (including The Cochrane Library...
Chronic hepatitis C infection affects nearly 300 million people worldwide. It is one of the main causes of chronic liver disease and the most common indication for liver transplantation.1-5 There are 6 major strains or genotypes of hepatitis C virus (HCV). These genotypes have different geographic distributions, with the type 1 genotype (HCV-1) most common in the United States (accounting for a...
The purpose of the present study was to develop stable lyophilized formulation peginterferon alfa-2b which is acquiescent short lyophilization process. evaluates effect buffering components and cryoprotectant(s) on depegylation in combination with Finally, a process identified can produce pharmaceutical form without any during long-term storage. Formulations were analyzed mainly for by HP-size ...
BACKGROUND The prevalence of hepatitis C in Iran is 1% and 18% in general population and thalassemia patients respectively. The cost effectiveness analysis of adding Ribavirin to Peginterferon alfa-2a (PEG IFN alfa-2a) as a combination treatment strategy of chronic hepatitis C in thalassemia patients in comparison with monotherapy could help clinicians and policy makers to provide the best trea...
OBJECTIVE Combination therapy with pegylated interferon (Peg) and ribavirin (RBV) is the standard of care for the treatment of chronic hepatitis C virus (HCV) infection. This analysis compares the cost efficacy of treatment with pegylated interferon alfa-2b plus ribavirin (Peg-2b plus RBV) with pegylated interferon alfa-2a plus ribavirin (Peg-2a plus RBV) in hypothetical cohorts of 100 chronic ...
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