background epidemiology of diseases changes over time with changes in socio-economic status, culture and health care systems. gastroesophageal reflux disease (gerd) and peptic ulcer disease (pud) are among the diseases whose epidemiology has changed over the past few decades in the west. studies addressing the trend of gerd and pud occurrence in iran are lacking. we aimed to look at the time tr...

conclusions about 90% of h. pylori strains potentially contained vaca s2m2 and s1m2 genotypes. infection with h. pylori strain containing the caga gene or the vaca s1m1 and s1m2 genotypes was associated with increased incidence of peptic ulcer disease (pud). objectives the aim of this study was to determine the frequency of two toxins and genotypes of vaca toxin in patients referred to a centra...

aim : the purpose of the present study was to evaluate the number and proportion of various causes of upper gastrointestinal bleeding and actual numbers of non-nsaid, non- helicobacter pylori ( h.pylori ) peptic ulcers seen in endoscopy of these patients. background : the number and the proportion of patients with non- h.pylori , non-nsaids peptic ulcer disease leading to upper gastrointestinal...

OBJECTIVES To show important aspects of gastroduodenal peptic ulcer and of Helicobacter pylori infection in children and adolescents. SOURCES Technical textbooks and MEDLINE and LILACS databases including publications between 1966 and 2006. SUMMARY OF THE FINDINGS The etiology of peptic ulcer in children and adolescents may be primary, associated with H. pylori infection, or secondary, in w...

INTRODUCTION Peptic ulcer is a lesion of the mucosal lining of the upper gastrointestinal tract characterized by an imbalance between aggressive and protective factors of the mucosa, having H. pylori as the main etiologic factor. Dietotherapy is important in the prevention and treatment of this disease. AIM To update nutritional therapy in adults' peptic ulcer. METHODS Exploratory review wi...

It has been suggested that the free radicals are closely related with peptic ulcer disease and gastritis. Although many studies have been undertaken to clarify the role of oxygen-derived free radicals, most of them were carried out animal models. The aims of this study were to assess the reactive oxygen species activity and the damage in Helicobacter pylori infected gastric mucosa in humans. In...

background: to asses the status of two representative genes of cag pai i.e caga and cage of helicobacter pylori strains infecting iranian patients suffered from various clinical outcomes using one-step pcr. methods: a total of 120 h. pylori infected patients including non-ulcer dyspepsia, nud (n=81), peptic ulcer disease, pud (n=17), and gastric carcinoma, gc (n= 22) referred for endoscopy or g...

background :   vaculating cytotoxic a ( vaca ) gene is one of the multiple helicobacter pylori genotypes that produce a cytotoxin protein (vaca).this gene is a major cause of chronic peptic ulcers and gastric cancer. the aim of this study was to determine the correlation between vaca gene with peptic ulcer disease (pud) and non-ulcer dyspepsia (nud).   methods :    this was a case control study...

hsematemesis and vomiting were regarded formerly as signs of peptic ulcer. They are known now to be utterly ^reliable as signs, both singly and collectively. The symptomatology of peptic ulcers needs to be written afresh on a clean slate, and more consideration paid to various conditions which mimic the symptoms On short refiection it is obvious that there is something radically ^rong. Duodenal...