BACKGROUND Pregnant women with Crohn's disease needs proper counselling about the effect of pregnancy and childbirth on their disease. However, Literature about the effect of childbirth on Crohn's disease is limited. This study examined the effect of childbirth on the course of Crohn's disease and especially perianal Crohn's disease. METHODS This is a retrospective cohort study which was perf...

BACKGROUND New sphincter-saving approaches have been applied in the treatment of perianal fistula in order to avoid the risk of fecal incontinence. Among them, the fibrin glue technique is popular because of its simplicity and repeatability. The aim of this review is to compare the fibrin glue application to surgery alone, considering the healing and complication rates. METHODS We performed a...

Background: Since 2007, ligation of the inter-sphincteric fistula tract (LIFT) has been performed successfully and enthusiastically to treat anal fistulas. However, whether a surgical treatment is better for trans-sphincteric still debated. The goal this study evaluate LIFT technique in treating perianal fistula. Methods: Our research consisted 40 cases with who presented our tertiary care cent...

BACKGROUND/PURPOSE This prospective study was designed to assess the safety, cost effectiveness, and advantages of performing posterior sagittal anorectoplasty without colostomy on girls with imperforate anus and rectovestibular fistula. METHODS Four girls with imperforate anus and rectovestibular fistula were entered into the study. Chest x-ray, renal ultrasound scan, and lateral fistulogram...

BACKGROUND Although many attempts have been made to advance the treatment of complex anal fistula, it continues to be a difficult surgical problem. This study aimed to describe the novel technique of video-assisted anal fistula treatment (VAAFT) and our preliminary experiences using VAAFT with patients with complex anal fistula. MATERIAL AND METHODS From May 2015 to May 2016, 52 patients with c...

Crohn's disease is a chronic inflammatory disorder that can affect any part of the gastrointestinal tract from the mouth to the anus. The disease is characterized by transmural inflammation that can be complicated by the development of fibrotic strictures, perforation, abscess formation, and fistulization. Perianal fistulas may arise from inflamed or infected anal glands (fistula-in-ano) and/or...

In the present modern day's world, anorectal disorders are increasing in number due to sedentary lifestyle. They cause great discomfort and make one’s life miserable. Among these fistula ano is most common. It challenging treat its recurrent nature. Fistula-in-ano an inflammatory tract that lined by unhealthy granulation tissue has two openings, external opening perianal skin internal anal cana...

Malignant transformation of fistulas in Crohn's disease (CD) patients is rare. Prior studies mainly focused on perianal fistulas as a complication of CD, and little is known about carcinoma in enterocutaneous fistulas. There are increasing concerns that chronic immunosuppression with azathioprine, widely used for remission maintenance and post-operative recurrence prevention in CD, could increa...

Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas. A 36-year-old male, diagnosed with Crohn's disease at the age of 24, developed adenocarcinoma in an anorectal fistula that had existed for years. He was treated with adjuvant chemoradiotherapy but died. A high index of suspicion and regu...

INTRODUCTION the low prevalence of enterocutaneous fistulas (ECF) in patients with Crohn´s disease (CD) justifies the scarcity of studies that analyze the effect of medical treatment and the need for surgery in these patients. The objective of this study was to evaluate the clinical characteristics of patients with CD who have ECF and the response to different treatments. MATERIALS AND METHOD...