The aim of this study was to examine the potential relationship between the occurrence of orthodontic root resorption and presence of dental anomalies such as tooth agenesis and pipette-shaped roots. Dental anomalies and root resorption were assessed on dental panoramic tomographs (DPT) of 88 subjects, 27 males and 61 females, mean age 28.4 (SD = 11.3 years), selected from orthodontic patients ...

Numerous animal and human studies have provided evidence supporting the belief that periodontal ligament stem cells (PDLSCs) can be harnessed for regeneration of periodontal tissues. Based on current literature on the use of ex vivo stem culture and associated problems, this case report describes a novel approach of direct application PDLSCs using stem cell assistance in periodontal regeneratio...

The gingiva is often the site of localized growths that are considered to be reactive rather than neoplastic in nature. Many of these lesions are difficult to be identified clinically and can be identified as specific entity only on the basis of typical and consistent histomorphology. Peripheral ossifying fibroma is one such reactive lesion. It has been described with various synonyms and is be...

Periodontal ligament stem cells (PDLSCs) are promising cell resource for the cell-based therapy for periodontitis and regeneration of bio-root. In this study, we investigated the effect of PDLSCs on neutrophil, a critical constituent of innate immunity, and the underlying mechanisms. The effect of PDLSCs on the proliferation and apoptosis of resting neutrophils and IL-8 activated neutrophils wa...

OBJECTIVE The purpose of this study was to use a Collagenase-Dispase assay to investigate the potential of a new storage media, coconut water, in maintaining viable periodontal ligament (PDL) cells on simulated avulsed teeth. STUDY DESIGN Fifty freshly extracted human teeth were divided into 3 experimental groups and 2 control groups. The positive and negative controls corresponded to 0 minut...

The biological mechanisms of tooth movement are based on the response of periodontal tissues to mechanical forces. The final result of these responses is remodeling of the extracellular matrix. Tissue reactions may vary depending upon the type, magnitude and duration of the applied forces. The purpose of the present study was to analyze the effects of centrifugal force on the transcription of c...

BACKGROUND Orthodontic tooth movement is a complex procedure that occurs due to various biomechanical changes in the periodontium. Optimal orthodontic forces yield maximum tooth movement whereas if the forces fall beyond the optimal threshold it can cause deleterious effects. Among various types of tooth movements intrusion and lingual root torque are associated with causing root resoprtion, es...

Human periodontal ligament fibroblasts and L 929 cell line labelled with chromium 51 were examined by electron microscope to evaluate the effect of the chromium labeling on the cell ultrastructure. The cells were labeled with chromium 12-20 hours before the start of the experiment. Af ter two and four hours of incubation at 37°C and 100% humidity, the cells were examined by scanning and transmi...

nerve endings have been described in extracted human teeth (Griffin and Harris, Australian DJ, 19:255-59, 1974; Harris and Griffin, Australian DJ, 19:174-81, 326-37, 1974), and in mouse molars with intact surrounding periodontium (Corpron et al., J Dent Res, 53-7S, 1974; Avery et al., J Dent Res, 54:92, 1975; Corpron et al. JDentRes, 57:1B224, 1977). l)uring previous investigations of periodont...

We prepared a cell sheet by using collagenase treatment to digest salmon atelocollagen fibrillar gel (SAC gel) on which human periodontal ligament (HPDL) cells had been cultured. The SAC gel was found to be digested completely within 2 h at a concentration of 50 U of collagenase per mg of collagen. The SAC gel on which HPDL cells were cultured for 10 d was treated with collagenase, resulting in...