Malignant peripheral nerve sheath tumors of the scalp are rare lesions of the nervous system. Only 14 cases have been reported to date. The field of neurosurgery has struggled with diagnosing and treating these tumors. In this report, we present two cases of giant malignant peripheral nerve sheath tumors of the scalp and retrospectively analyze the clinical features, imaging findings, pathologi...

background: the standard method for repair of an injured peripheal nerve is epineural repair with separate sutures. herein we describe a method in which the nerve is sutured with continous sutures. in fact this method has not been utilized for nerve repair previously and our purpose was to compare it to the standard method. if it proved to be successful it would replace the standard method in c...

Malignant peripheral nerve sheath tumour (MPNST) is a very rare entity in head and neck with high rate of recurrences and local invasiveness. This tumour is usually found in lower extremities and only 10-12% occur in head and neck region. The diagnosis is considered as the most elusive and difficult among soft tissue sarcomas because of its non specific presentation, both clinically as well as ...

Schwannoma is the most common nerve sheath tumor in the posterior mediastinum, whereas intrathoracic paraspinal malignant peripheral nerve sheath tumor (MPNST) is quite rare. Both benign and malignant nerve sheath tumors may be symptomatic, rendering clinical differentiation of limited utility. On radiographic imaging, erosion of the ribs and vertebral bodies, irregularity in contour, and inhom...

Nerve sheath myxoma has been described as a rare neural tumor arising from Schwann cells. It is observed most frequently in the central area of the face, neck and upper extremities. In the past the term neurothekeoma was used as synonym for nerve sheath myxoma but according to new reports, they are separate entities which can be confirmed by immunohistochemistry as in our case. Oral involvement...

BACKGROUND AND IMPORTANCE Malignant peripheral nerve sheath tumors are the most common malignant mesenchymal tumors of soft tissues, but they are very rare when found to arise from a cranial nerve and when not in association with neurofibromatosis. These tumors are highly malignant and carry a poor prognosis with survival usually less than 6 months. CLINICAL PRESENTATION The authors report th...

Myelin sheath geometry, encompassing myelin sheath thickness relative to internodal length, is critical to optimize nerve conduction velocity and these parameters are carefully adjusted by the myelinating cells in mammals. In the central nervous system these adjustments could regulate neuronal activities while in the peripheral nervous system they lead to the optimization and the reliability of...

Malignant peripheral nerve sheath tumors are extremely rare soft tissue sarcomas. Among various locations, the trunk and extremities are the most commonly involved sites, with only 15% of such lesions occuring in head and neck region. Here, we report a case of a 74-year-old male who presented with forehead swelling and right eye deviation. Computed tomography images revealed a tumor involving t...

Malignant peripheral nerve sheath tumors originating from the parotid gland are extremely rare. A 76-year-old male patient underwent an incisional biopsy for an ulcerated mass in the anteroinferior aspect of the left auricle. The diagnosis was made as malignant mesenchymal tissue sarcoma, but the patient refused treatment. Upon progressive growth of the mass within two months, he underwent a pa...