vincristine (vcr) as a frequently used antimitotic agent which is commonly prescribed for wide spectrum of neoplasm, causes mixed sensorimotor neuropathy. several evidences show lithium could be a neuroprotective agent, therefore to assess whether a pretreatment and at subtherapeutic dose it could prevent the peripheral neuropathy produced by vcr, rats were treated with vcr 0.1mg/kg i.p. for 3 ...

peripheral blood stem cell transplantation (pbsct) is an effective treatment for hematological malignancies. mobilization of peripheral blood progenitor cells performs in different ways among transplantation centers. forceful mobilization schedules are comprised of growth factor alone, chemotherapy along with growth factor and also, a newly combination of novel agent such as plerixafor with any...

a common cause of peripheral nerve injury is trauma. the positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. in this experiment, the effect of intraperitoneal administration of ubiquinone (coq10) on an acute experimentally sciatic nerve crush was studied in a rat model. forty-five male wistar rats, weighing between 160-180 g were u...

The sense of limb position is crucial for movement control and environmental interactions. Our understanding of this fundamental proprioceptive process, however, is limited. For example, little is known about the accuracy of arm proprioception: Does it vary with changes in arm configuration, since some peripheral receptors are engaged only when joints move toward extreme angles? Are these varia...

Our goal is to link spatial and temporal properties of letter recognition to reading speed for text viewed centrally or in peripheral vision. We propose that the size of the visual span the number of letters recognizable in a glance imposes a fundamental limit on reading speed. and that shrinkage of the visual span in peripheral vision accounts for slower peripheral reading. In Experiment 1, we...

based on the conducted anatomic studies at our institutions as well as clinical experience with migraine surgery, we have refined our onobotulinumtoxin a (botox®) injection techniques. pain management physicians are in unique position to be able to not only treat migraine patient, but also to be able to collaborate with neurologists and peripheral nerve surgeons in identifying the migraine trig...

Technological and economic innovations cannot respond to all social challenges. Natural material resources are becoming ever scarcer, so it is necessary use investment assets, maximizing efficiency. It a major task address the backwardness originating from regional disparities create opportunities for catching up in peripheral regions. The study, based on process-oriented model defined our prev...