نتایج جستجو برای: personalised medicine

تعداد نتایج: 255238  

Journal: :Progress in Nuclear Magnetic Resonance Spectroscopy 2017

2014
Gabriele Weiler Christina Schröder Fatima Schera Matthias Dobkowicz Stephan Kiefer Karsten R Heidtke Stefanie Hänold Iheanyi Nwankwo Nikolaus Forgó Martin Stanulla Cornelia Eckert Norbert Graf

Biobanks represent key resources for clinico-genomic research and are needed to pave the way to personalised medicine. To achieve this goal, it is crucial that scientists can securely access and share high-quality biomaterial and related data. Therefore, there is a growing interest in integrating biobanks into larger biomedical information and communication technology (ICT) infrastructures. The...

Journal: :The European respiratory journal 2007
J A Bakker J Bierau M Drent

D rug-induced pulmonary toxicity is a serious and expanding problem [1, 2]. Since the mid 1980s, the understanding of the metabolism of pharmaceuticals has increased substantially. Not least because of the introduction of molecular biological techniques, defects in drug-metabolising pathways have been elucidated. Nowadays, pharmacogenetics can guide the clinician in the choice of the best thera...

2012
Vinit Sawhney Scott Brouilette Dominic Abrams Richard Schilling Benjamin O’Brien

Cardiovascular disease (CVD) is a heterogeneous, complex trait that has a major impact on human morbidity and mortality. Common genetic variation may predispose to common forms of CVD in the community, and rare genetic conditions provide unique pathogenetic insights into these diseases. With the advent of the Human Genome Project and the genomic era, new tools and methodologies have revolutioni...

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