Reliably differentiating brown adipose tissue (BAT) from other tissues using a non-invasive imaging method is an important step toward studying BAT in humans. Detecting BAT is typically confirmed by the uptake of the injected radioactive tracer 18F-Fluorodeoxyglucose (18F-FDG) into adipose tissue depots, as measured by positron emission tomography/computed tomography (PET-CT) scans after exposi...

OBJECTIVES ¹⁸F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) is a less invasive diagnostic tool and promising in detecting gastrointestinal lesions of pediatric inflammatory bowel disease (IBD) patients. Co-registration of low-dose computed tomography (CT) could lead to improvements in the assessment of disease. Therefore, this retrospective study evaluates the value of PET±CT in ...

Due to its chemical inertness and physical properties PET is particularly suitable for food packaging applications, especially for drinking water. More bottled water is consumed than other bottled beverages. This article is a survey and toxicological investigation of chemical compounds, which are able to diffuse from PET bottles to water. The exact detailed chemical composition of plastic mater...

The exposome is a complement to the genome that includes non-genetic causes of disease. Multiple definitions are available, with salient points being global inclusion of exposures and behaviors, and cumulative integration of associated biologic responses. As such, the concept is both refreshingly simple and dauntingly complex. This article reviews high-resolution metabolomics (HRM) as an afford...

OBJECTIVE To determine the role of environmental pollutants in the etiology of nasal polyposis. DESIGN Case-control study. SETTING A community-based hospital practice in the Gaspesian peninsula in rural northeastern Quebec. PATIENTS Fifty-five case patients with nasal polyposis and 55 age-matched control subjects without nasal polyposis who were seen at one physician's practice (J.K.) fro...

Pesticides, common environmental exposures, have been examined in relation to breast cancer primarily in occupational studies or exposure biomarker studies. No known studies have focused on self-reported residential pesticide use. The authors investigated the association between reported lifetime residential pesticide use and breast cancer risk among women living on Long Island, New York. They ...

Atopic dermatitis (AD) in young children is often followed by the development of asthma (atopic march). The role of environmental exposures is unclear in this high-risk population. We aimed to determine the predictive relationship between indoor allergen exposures, particularly pets, rodents, and cockroaches, to the development of asthma in a prospective pediatric cohort. Children with AD and a...

ownership and allergic disease, leading to the widely accepted recommendation of refraining or removal of pets from the home. The current study, as well as others, found that pet ownership may have a protective effect against the development of allergic disease. Children who were exposed to pets at birth had a lower prevalence of allergic rhinitis, asthma, and infant eczema, although this study...

Mediastinal fibrosis is a rare, benign disorder characterised by proliferation of fibrous tissue within the mediastinum. It can present as diffuse mediastinal infiltration or, more frequently, as a localised soft tissue mass, usually in the right paratracheal or subcarinal areas. 18-fluorodeoxyglucose (18-FDG) positron emission tomography (PET) imaging has only been reported in a few case repor...