UNLABELLED The renin angiotensin system (RAS) has been implicated as one mediator of the cardiovascular effects of estrogen. Since changes in angiotensin type 1 (AT(1)) receptor expression are central to modulation of the RAS, we used the noninvasive PET imaging technique to study for the in vivo effects of estrogen on membrane and intracellular AT(1) receptors. METHODS Dynamic PET measuremen...

A clinical prototype of combined Combined Positron Emission Tomography (PET) / Computed Tomography (CT) system went under the clinical evaluation in 1998. After three years of research and clinical evaluation first clinical combined PET/CT system was installed in a clinic in 2001 [1-3]. Gradually clinical utilization of combined PET/CT increased tremendously particularly in oncological imaging ...

Introduction Efforts to combine anatomical and functional imaging modalities have resulted in the successful development and widespread use of PET/CT systems. PET/MRI would offer substantially better soft tissue contrast, provide high-resolution anatomical information and would be beneficial for longitudinal studies. Combining conventional PET and superconducting MRI faces many technical challe...

PURPOSE To evaluate the accuracy and biological basis for [(11)C]choline-PET-CT in the nodal staging of high risk localized prostate cancer patients. EXPERIMENTAL DESIGN Twenty-eight patients underwent dynamic [(11)C]choline-PET-CT of the pelvis and lower abdomen prior to extended laparoscopic pelvic lymph node dissection (eLPL). The sensitivity and specificity of [(11)C]choline PET, [(11)C]c...

Purpose: To evaluate the accuracy and biological basis for [C]choline-PET-CT in the nodal staging of high risk localized prostate cancer patients. Experimental Design: Twenty-eight patients underwent dynamic [C]choline-PET-CT of the pelvis and lower abdomen prior to extended laparoscopic pelvic lymph node dissection (eLPL). The sensitivity and specificity of [C]choline PET, [C]choline PET-CT, a...

objective(s) tuberculosis (tb) is the leading cause of mortality among the infectious diseases, especially in developing countries. one of the main goals in tuberculosis research is to identify antigens which have the ability of inducing cellular and/or humoral immunity in order to use them in diagnostic reagents or vaccine design. the aim of this study was to clone and express the tb'0.4 ...

In this work, ternary polymer blends based on polypropylene (PP)/ polyethylene terephthalate (PET) /poly(styrene-b (ethylene-co-butylene)-b-styrene) (SEBS) triblock copolymer and a reactive maleic anhydride grafted SEBS (SEBS-g-MAH) at various compositions were prepared by co-rotating twin screw extruder. The effects of PET, SEBS and SEBS-g-MAH compatibilizer on morphology of the blends were ex...

PURPOSE Positron Emission Tomography (PET) imaging of HER2 expression could potentially be used to select patients for HER2-targed therapy, predict response based on uptake and be used for monitoring. In this phase I/II study the HER2-binding Affibody molecule ABY-025 was labeled with (68)Ga-gallium ([(68)Ga]ABY-025) for PET to study effect of peptide mass, test-retest variability and correlati...

citrus tristeza virus (ctv) is among the most destructive pathogens of citrus and causes substantial economic losses in citrus-growing industry worldwide. considering recent distribution of this pathogen and its capability of transmission by existing aphid vectors in iran, detection of this virus is enforceable for controlling the damage caused by this pathogen in iran, as one of the major citr...