Results Ready-to-use system provided patients with very fast, easy to perform and safe CRP measurement, having obtained reliable results. Children and their parents found avoidance of frequent outpatient clinic visits and painful collection of blood from veins extremely important. Parents were able to use the system properly just after 2-3 hours of practical training. Regular, up to twice a day...

Fever is defined periodic/recurrent in presence of three or more episodes of fever of unknown origin that occur in a period of six months and whose onset is at least one week apart from each other. The diagnosis, often complex, should exclude an infectious cause and an onco-haematological disease. History and physical examination are essential to make a diagnostic hypothesis of a periodic fever...