It lhas been possible to miniatuirize the glass pH electrode to an extent tllat it can be uised to measture the intraltiminal pH of single mammalian nephrons(l). There are, however, a nutmber of problems that arise from the miniaturization process. Thlese includ(le electrode insulation, the incorporation of a suitable reference electrode witlh the pH glass electrode, an(d the ultimate achievabl...