TASK-2 (KCNK5 or K(2P)5.1) is a background K(+) channel that is opened by extracellular alkalinization and plays a role in renal bicarbonate reabsorption and central chemoreception. Here, we demonstrate that in addition to its regulation by extracellular protons (pH(o)) TASK-2 is gated open by intracellular alkalinization. The following pieces of evidence suggest that the gating process control...

This study investigates the effect of electrocoagulation contact time on pH and TSS wastewater discharged from treatment plant (WWTP) Psychiatric Hospital West Java Province. The experiment followed pretest-posttest control group design. involved testing 56 samples six times before after treatment. Each was repeated four times, there one for each repetition. tool used in this consisted 1-mm ele...

pH neutralization reaction process plays a crucial role in Waste Water Treatment Process (WWTP). Traditional PID Proportion Integral Differential, (or even advanced control) algorithms have poor performance on WWTP due to the strong non-linearity, large time lag, and inertia characteristics of neutralization. Therefore, finding superior control method maintain value wastewater within normal ran...

A method is described for the determination of the pH of intracellular water based on the distribution of [14C]benzoate (0.01 mM) between intra- and extra-cellular water. Benzoate at higher concentrations (2-10mM) enters the yeast cell in the undissociated form, and its neutralization within the cell can cause a shift of the pH of the intracellular water by more than 1 pH unit. Benzoate causes ...

The hemagglutinin of influenza virus undergoes a conformational change at low pH, which results in exposure of a hydrophobic segment of the molecule, crucial to expression of viral fusion activity. We have studied the effects of incubation of the virus at low pH either at 37 or 0 degrees C. Treatment of the virus alone at pH 5.0 induces the virus particles to become hydrophobic, as assessed by ...

An indirect hemagglutination test for a seroepidemiological survey of Streptococcus pyogenes infection was standardized. This is an improved modification of the indirect hemagglutination test which utilizes an unstable reagent prepared with fresh blood cells. Two types of bacterial antigens represented by extracellular products and purified streptolysin O were assayed, but only the former antig...

The use of Recurrent Neural Networks (RNNs) for system identification has recently gathered increasing attention, thanks to their black-box modeling capabilities.Albeit RNNs have been fruitfully adopted in many applications, only few works are devoted provide rigorous theoretical foundations that justify control purposes. aim this paper is describe how stable Gated Units (GRUs), a particular RN...

a comprehensive study on the chemical composition of rainwater was carried out in obuasi, a gold mining town in ghana. rainwater samples were analyzed for major ions (ca2+,mg2+, k+, na+, nh4+, cl-, no3- and so4 2-) and trace metals (fe, al, zn, pb, cr, and cd). the rainwater was typically acidic with a mean ph of 4.76±0.47, which ranged from 4.0 to 5.6. the low ph found in the water suggests t...

measles is one of the most contagious human diseases. although mass vaccination programs have reduced the incidence of this disease, measles is still an important cause of morbidity and mortality among children in developing countries. therefore the use of sensitive techniques to evaluate vaccine efficacy and level of immunity among members of susceptible communities is crucial. serum neutraliz...