OBJECTIVES Microencapsulation of drugs into preformed polymers is commonly achieved through solvent evaporation techniques or spray drying. We compared these encapsulation methods in terms of controlled drug release properties of prepared microparticles and investigated the underlying mechanisms responsible for the 'burst release' effect. METHODS Using two different pH-responsive polymers wit...

The review focuses on responsive/switching behavior of polymer brushes. The structure of the polymer brushes is analyzed in terms of the constitution and conformation of polymer chains. Responsive properties are widely discussed based on phase transition mechanisms in a controlled environment when changes are induced by solvent quality, temperature, concentration of ions, and interactions with ...

This thesis discusses innovative approaches to polymer-based photonic coatings, with the present chapter presenting an overview of developments in this field. The coatings in question can change their topological properties in a reversible, dynamic way when exposed to an external stimulus. This thesis will first describe photoresponsive coatings that change their surface topography and therefor...

Responsive polymer thin films play an important role as structural components in the emerging fields of soft actuators, wearable electronics, and biomedical devices. These are capable changing their physical and/or chemical properties significantly response to environmental stimuli, such temperature, light, pH, magnetic fields, ion strength. The integration multifunctional designs networks enab...

Introduction Stimuli-responsive gels that exhibit swelling/shrinking changes in response to environmental changes such as pH and temperature have many future opportunities as suitable materials for mimicking biomolecules and designing smart systems in the biochemical and biomedical fields [1]. For example, self-regulated drug delivery can be achieved by loading a drug within pHand temperature-r...

Anticancer drug delivery strategies are designed to take advantage of the differential chemical environment in solid tumors independently, or high levels reactive oxygen species (ROS) low pH, compared healthy tissue. Here, design and thorough characterization two functionalizable “AND gate” multiresponsive (MR) block amphiphilic copolymers reported, aimed full coexistence cues—ROS pH—present tu...

Modified poly(aspartic acid)/poly(vinyl alcohol) interpenetrating polymer network (KPAsp/PVA IPN) hydrogel for drug controlled release was synthesized by a simple one-step method in aqueous system using poly(aspartic acid) grafting 3-aminopropyltriethoxysilane (KH-550) and poly(vinyl alcohol) (PVA) as materials. The hydrogel surface morphology and composition were characterized by Fourier trans...