Sterile dosage forms are pharmaceutical preparations that require to be free of microorganisms and particles. In health services, sterile often undergo a series changes in form from their original conditions new products through dissolution or mixing with other preparations. To maintain sterility, preparation dispensing skills needed. Regulation the Minister Health Republic Indonesia No. 72 201...

Strained rings are increasingly important for the design of pharmaceutical candidates, but cross-coupling strained remains challenging. An attractive, underdeveloped, approach to diverse functionalized carbocyclic and heterocyclic frameworks containing all-carbon quaternary centers is coupling abundant strained-ring carboxylic acids with aryl halides. Herein we disclose development a nickel-cat...

OVERVIEW The plasma supply for pharmaceutical manufacturing consists of surplus plasma recovered from whole blood collection and source plasma from plasmapheresis in Korea. Shortages are typically covered by importation. The total plasma supply for fractionation was 608,352 liters in 2009, of which 430,267 liters were supplied domestically. The self-sufficiency rate was, therefore, about 71% in...

With the prevalence of dementia expected to exceed 115 million worldwide by 2050 [1], stakeholders across all sectors of society recognize the need for an aggressive, coordinated, and global response. Similar challenges have been faced in the past and provide models for how to mount an effective response today. In the mid-1950s and early 1960s, patient advocacy organizations, pharmaceutical com...

BACKGROUND Academic medical centers are examining relationships with the pharmaceutical industry and making changes to limit interactions. Most doctors, however, practice outside of academic institutions and see pharmaceutical detailers and accept drug samples and gifts. Little guidance for practicing physicians exists about transforming practices to become pharma-free. Consideration must be gi...

Conflicts of interest between physicians' commitment to patient care and the desire of pharmaceutical companies and their representatives to sell their products pose challenges to the principles of medical professionalism. These conflicts occur when physicians have motives or are in situations for which reasonable observers could conclude that the moral requirements of the physician's roles are...

OBJECTIVES Publicly funded addiction treatment organizations have been slow to adopt pharmacotherapies. Few studies have examined the organizational factors associated with adoption of different types of medication in this treatment sector. This study identifies organization-level facilitators and barriers to the use of medications in publicly funded addiction treatment organizations. METHODS...

Currently in Europe, approximately 30 million people suffer from rare diseases, and a major problem is that many patients do not have access to quality healthcare for their disorders. Moreover, there is also a lack of quality information and a networking system aimed at supporting interaction among patients, clinicians, researchers, pharmaceutical industries, and governmental bodies. The purpos...

The effects of magnesium stearate (MgSt) and shear stress on flow properties and hydrophobicity are not well known. Blends with different concentrations of magnesium stearate and varying amounts of shear were tested using three different procedures: the FT4 Rheometer test, a tap density analyzer, and the Washburn method, to better understand the relation of lubricant concentration, amount of sh...