نتایج جستجو برای: pharmacological technique

تعداد نتایج: 683340  

Journal: :Indonesian Midwifery and Health Sciences Journal 2022

Background : Back pain during pregnancy was experienced by many women at certain times their pregnancy, usually in the third trimester of pregnancy. Efforts to reduce can use pharmacological and non-pharmacological methods, providing anti-pain drugs carried out health workers methods be done or families, one which is endorphin massage therapy. The purpose this study determine effect Endorphin M...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بوعلی سینا - دانشکده علوم پایه 1392

اکسیدهای آهن ترکیبی شیمیایی از آهن و اکسیژن می باشند. بطور کلی 16 نوع ترکیب شناخته شده از اکسیدها و هیدروکسیدهای آن وجود دارد. در میان این اکسیدها، آهن 3 اکسید(fe2o3) بسیار مورد توجه است. این اکسید خود از چهار فاز متفاوت آلفا، بتا، گاما و اپسیلون با ویژگیهای منحصر به فرد تشکیل شده است. فاز گامای این اکسید (?- fe2o3)، مگهمایت نام دارد که ساختاری کریستالی و ایزومتریک داشته و فری مغناطیس است. این ...

Journal: :Journal of visualized experiments : JoVE 2017
Jan Lukas Anne-Marie Knospe Susanne Seemann Valentina Citro Maria V Cubellis Arndt Rolfs

The use of personalized medicine to treat rare monogenic diseases like lysosomal storage disorders (LSDs) is challenged by complex clinical trial designs, high costs, and low patient numbers. Hundreds of mutant alleles are implicated in most of the LSDs. The diseases are typically classified into 2 to 3 different clinical types according to severity. Moreover, molecular characterization of the ...

2014
Joseline Ratnam Barbara Zdrazil Daniela Digles Emiliano Cuadrado-Rodriguez Jean-Marc Neefs Hannah Tipney Ronald Siebes Andra Waagmeester Glyn Bradley Chau Han Chau Lars Richter Jose Brea Chris T. Evelo Edgar Jacoby Stefan Senger Maria Isabel Loza Gerhard F. Ecker Christine Chichester

Integration of open access, curated, high-quality information from multiple disciplines in the Life and Biomedical Sciences provides a holistic understanding of the domain. Additionally, the effective linking of diverse data sources can unearth hidden relationships and guide potential research strategies. However, given the lack of consistency between descriptors and identifiers used in differe...

2015
D. Malfacini C. Ambrosio M. C. Gro’ M. Sbraccia C. Trapella R. Guerrini M. Bonora P. Pinton T. Costa G. Calo’ James Porter

Nociceptin/orphanin FQ (N/OFQ) controls several biological functions by selectively activating an opioid like receptor named N/OFQ peptide receptor (NOP). Biased agonism is emerging as an important and therapeutically relevant pharmacological concept in the field of G protein coupled receptors including opioids. To evaluate the relevance of this phenomenon in the NOP receptor, we used a biolumi...

2011
Xiaoyang Wu Evan Katz Maria Cecilia Della Valle Kirsten Mascioli John J Flanagan Jeffrey P Castelli Raphael Schiffmann Pol Boudes David J Lockhart Kenneth J Valenzano Elfrida R Benjamin

Fabry disease is caused by mutations in the gene (GLA) that encodes α-galactosidase A (α-Gal A). The iminosugar AT1001 (GR181413A, migalastat hydrochloride, 1-deoxygalactonojirimycin) is a pharmacological chaperone that selectively binds and stabilizes α-Gal A, increasing total cellular levels and activity for some mutant forms (defined as "responsive"). In this study, we developed a cell-based...

Journal: :Annals of clinical and laboratory science 2013
Grazyna Chwatko

Thiols have been of enduring interest for many years because of their role in biological and pharmacological processes. Monitoring of total thiols content is very important in order to understand their function in living organisms. This paper describes the spectrophotometric method for the determination of total thiols concentration in urine. The method is based on derivatization with 1-benzyl-...

Journal: :NeuroImage 2001
R Kalisch G K Elbel C Gössl M Czisch D P Auer

Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-dependent (BOLD) contrast is now increasingly applied for measuring drug effects on brain activity. A possible confound in pharmacologic fMRI (phMRI) is that the BOLD signal may be sensitive to systemic cardiovascular or respiratory parameters, which can themselves be modulated by a drug. To assess whether abrupt cha...

Journal: :BMC medical education 2015
Patrik Aronsson Shirley Booth Staffan Hägg Karin Kjellgren Ann Zetterqvist Gunnar Tobin Margareta Reis

BACKGROUND The overall aim of the study was to explore health care students´ understanding of core concepts in pharmacology. METHOD An interview study was conducted among twelve students in their final semester of the medical program (n = 4), the nursing program (n = 4), and the specialist nursing program in primary health care (n = 4) from two Swedish universities. The participants were indi...

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