Lipid nanocapsules (LNCs) represent a stable, biocompatible and worthwhile drug delivery system, demonstrating significant potential as gene/drug delivery platforms for cancer therapy. Imatinib, a potent tyrosine kinase inhibitor, has revolutionized the therapy of malignancies resulting from abnormal tyrosine kinase activity. However, its Clinical effectiveness in cancer treatment is h...

Lipid nanocapsules (LNCs) represent a stable, biocompatible and worthwhile drug delivery system, demonstrating significant potential as gene/drug delivery platforms for cancer therapy. Imatinib, a potent tyrosine kinase inhibitor, has revolutionized the therapy of malignancies resulting from abnormal tyrosine kinase activity. However, its Clinical effectiveness in cancer treatment is h...

Shear-wave velocity ( ) is an important parameter used for site characterization in geotechnical engineering. However, dispersion curve inversion is challenging for most inversion methods due to its high non-linearity and mix-determined trait. In order to overcome these problems, in this study, a joint inversion strategy is proposed based on the particle swarm optimization (PSO) algorithm. The ...

Seismic inversion is a method that extracts acoustic impedance data from the seismic traces. Source wavelets are band-limited, and thus seismic traces do not contain low and high frequency information. Therefore, there is a serious problem when the deterministic seismic inversion is applied to real data and the result of deterministic inversion is smooth. Low frequency component is obtained fro...

Knowledge about structural variation in the human genome has grown tremendously in the past few years. However, inversions represent a class of structural variation that remains difficult to detect. We present a statistical method to identify large inversion polymorphisms using unusual Linkage Disequilibrium (LD) patterns from high-density SNP data. The method is designed to detect chromosomal ...

Despite the significant advances made over the last few years in mapping inversions with the advent of paired-end sequencing approaches, our understanding of the prevalence and spectrum of inversions in the human genome has lagged behind other types of structural variants, mainly due to the lack of a cost-efficient method applicable to large-scale samples. We propose a novel method based on pri...

shear-wave velocity ( ) is an important parameter used for site characterization in geotechnical engineering. however, dispersion curve inversion is challenging for most inversion methods due to its high non-linearity and mix-determined trait. in order to overcome these problems, in this study, a joint inversion strategy is proposed based on the particle swarm optimization (pso) algorithm. the ...