Materials: Ethylene oxide (all materials Sigma Aldrich unless stated) was dried over CaH 2 , purified through n-BuLi twice for 30 min at-10 0 C and was then distilled into an appropriately calibrated Pyrex ampule for use. Phosphazene base (P 4-t-Bu) (1M solution in hexane), sec-BuLi (1.4 M solution in cyclohexane) and acetic acid (Panreac) were used without further purification. Benzene (Chem L...

Energy preservation is one of the most important research challenges in Wireless Senor Networks (WSNs). In recent research, topologies and architectures have investigated that allow energy efficiency in WSNs. Clustering is one of the most famous energy efficient techniques. In clustering, the selection of cluster head (CH) and short distance multi-hop energy efficient communication between CH a...

The need to enhance the immunogenicity of purified subunit antigens and modulate resulting immune responses has prompted the development of new adjuvants. Here, the ability of CpG oligodeoxynucleotides (ODN), a bovine host defence peptide indolicidin, and polyphosphazene to synergistically combine and enhance innate and adaptive immune responses was examined in mice. In vitro, the adjuvant comb...

In this work, we report a large scale synthetic procedure that allows attachment of magnetite nanoparticles onto Ag NWs in situ, which was conducted in a triethylene glycol (TREG) solution with iron acetylacetonate and Ag NWs as starting materials. The as-prepared Ag NW/Fe3O4 NP composites are well characterized by SEM, TEM, XRD, XPS, FT-IR, and VSM techniques. It was found that the mass ratio ...

In this study, we have been involved in the synthesis and characterization studies of a new cyclotriorganophosphazenes complex with protected phloroglusine ligand. Firstly,we synthesized hexachlorocyclotirphosphazene from ammonium chloride and phosphorus pentachloride reaction and then two hydroxyl groups of the phloroglusine ligand were protected with methyl iodide and tosyl chloride. Fina...

Whooping cough is a respiratory illness most severe in infants and young children. While the introduction of whole-cell (wP) and acellular pertussis (aP) vaccines has greatly reduced the burden of the disease, pertussis remains a problem in neonates and adolescents. New vaccines are needed that can provide early life and long-lasting protection of infants. Vaccination at an early age, however, ...

Respiratory syncytial virus (RSV) is the most common cause of respiratory tract infections in both children and elderly people. In this study we evaluated the short- and long-term protective efficacy of a single intranasal (IN) immunization with a RSV vaccine formulation consisting of a codon-optimized fusion (F) protein formulated with poly(I:C), an innate defense regulator peptide and a polyp...