Background: Green meniran plant (Phyllanthus niruri Linn) is traditionally believed to treat many diseases, such as reducing fever, diarrhea, cough with phlegm, inflammation, malaria, and acne. This research aims determine the class of compounds active in ethanol extract green leaf.Methods: An experimental study was conducted using phytochemical testing includes qualitative quantitative tests i...

Objetivo: Realizar análise fitoquímica dos metabolismos secundários da raiz e folha Planta Phyllanthus Niruri L. (Quebra-pedra). Métodos: Os procedimentos experimentais, bem como a seguiram as recomendações evidenciadas no manual de Barbosa et al., (2001) intitulado “Manual Para Análise Fitoquímica Cromotográfica Extratos Vegetais”. A coleta planta vulgo “quebra-pedra” se deu partir do mês març...

Abstract Phyllanthus niruri L. (meniran), the member of Euphorbiaceae , is a medicinal plant that commonly found in tropical and sub-tropical areas such as Asia, America, China. Various factors environment, geographical location, harvest time, post-harvest process can affect quality crude drugs produced from P. . The objective this study was to evaluate meniran herbs obtained 15 origins East Ce...

The asymmetric synthesis of the new lignan cubebin dimethyl ether was accomplished in eight steps with an overall yield of 40 %. In addition, the known lignans (+)-hinokinin and (+)-dihydrocubebin were synthesized by this route. Our approach involves the highly diastereoselective and enantioselective (de ≥ 98%, ee ≥ 98%) construction of a trans-substituted 2,3dibenzylbutyrolactone through an as...

The effects of aqueous (PnAq) and alcoholic (PnA1 extract (50-250 mg/kg) of P. niruri on in vivo gamma radiation induced chromosome aberration and in vitro antioxidant activity (50-500 microg/ml) were studied. The antioxidant activity was studied by measuring inhibition of hydroxyl radicals generated by the fenton reaction along with pro-oxidant and iron chelating ability. PnA1 showed highly si...