BACKGROUND AND AIMS Environmental exposures to chrysotile and tremolite from the soil cause pleural plaques and mesothelioma in northeast Corsica. Goats grazing in the contaminated areas inhale asbestos fibres. We used this natural animal model to study whether these exposures actually result in increased fibre burdens in the lungs and parietal pleura. METHODS Ten goats from areas with asbest...

1. The number of muscle fibres innervated by individual motor neurones (motor unit size) was measured in lumbrical muscles of rats aged 0--28 days, during the period of elimination of polyneuronal innervation. Motor unit sizes were determined from twitch tension measurements combined with muscle fibre counts made from histological sections of the muscles. 2. The relative tensions contributed by...

1. Using conventional microelectrode techniques for the intracellular recordings of the membrane potential, the effects of labetalol were studied on cardiac Purkinje, atrial and ventricular muscle fibres of the dog. 2. Labetalol (1-10 microM) reduced, in a concentration-dependent manner, the action potential amplitude (APA) and the maximum rate of rise of the action potential (Vmax) in Purkinje...

The incidence of hyper-contracted giant fibres in pig postmortem skeletal muscle is closely related to poor meat quality in terms of pale, soft, and exudative pork. Detection of a predisposition to develop giant fibres in live pigs could help to predict pork quality and to exclude affected pigs from genetic selection. The abundance and proportion of giant fibres in longissimus muscle were highe...

The surface chemical analysis and bulk analysis were conducted for fibres regenerated from waste garments and treated with iodine solution. The aim was to assess the fibre accessibility by the iodine solution and ascertain the location of the reagent within the fibres. X-ray Photoelectron Spectroscopy (XPS) analysis indicated that the fibres regenerated from indigo dyed waste denim garments (Re...

The main modelling methods devoted to microstrutured air-silica optical fibres (MOFs) are presented and discussed. Then, the specific propagation properties of MOFs are studied in detail. Characteristics measured on fibres manufactured in our laboratory or reported in the literature are analysed. A large number of potential and demonstrated applications are presented and the obtained performanc...

Muscle fibres of the locust extensor tibiae (jumping muscle) were examined by interference microscopy and by electron microscopy. The electrical responses of single fibres and the mechanical responses of bundles or selected regions to the nerve fibres were examined. Four axons innervate the muscle: fast (FETi), slow (SETi), common inhibitor (CI) and dorsal unpaired median (DUMETi). Their distri...

In a study of the mortality experience of 6931 employees of two New Orleans asbestos cement products manufacturing plants over 95% were traced. Chrysotile was the primary fibre used in both plants. Plant 1 also used small amounts of amosite and, later, crocidolite irregularly whereas plant 2 used crocidolite steadily in pipe production. Previously reported exposure concentration estimates were ...