Quinolone antibiotics have been commonly used to treat cases of multiple antibiotic resistance. Unfortunately, quinolone so much resisted by infectious bacterial agents. This study aimed evaluate the susceptibility some clinical isolates E. coli and determination plasmid-encoded resistance genes.
 Our results showed plasmid quinolone-resistance genes in following prevalence: qnr genes: S (...

pseudomonas aeruginosa is an important life-threatening nosocomial pathogen and plays a prominent role in serious infections in burned patients. the current study was undertaken to characterize p. aeruginosa strains isolated from burned patients in tehran, iran. the study was conducted in a major burn center in tehran, iran in 2007. a total of seventy specimens obtained from different clinical ...

background and purpose: brain-derived neurotrophic factor (bdnf) is present in the hippocampus and cerebral cortex in high concentrations and has an important role in development, maintenance and regeneration of the nervous system. the aim of this study was to produce active bdnf in e.coli using transforming plasmid. methods: to construct an expression plasmid of bdnf, a gene coding for it was ...

Minicircles are non-viral delivery vectors with promising features for biopharmaceutical applications. These plasmid-derived circular DNA molecules that obtained in vivo Escherichia coli by the intramolecular recombination of a parental plasmid, which generates minicircle containing eukaryotic therapeutic cassette interest and miniplasmid prokaryotic backbone. The production process results thu...

other Rhizobium species. Most of these plasmids encoding for fixation and nodulation properties are non-self transmissible. Plasmid profiles were determined for 24 strains of R. trifolii. All the strains harboured at least three plasmids and as many as eight were present in some strains. Southern hybridization with cloned R. meliloti nifgenes was used to identify indigenous Nif plasmids. Each s...