نتایج جستجو برای: platinum group elements

تعداد نتایج: 1249980  

Journal: :Lung cancer 2005
T Le Chevalier G Scagliotti R Natale S Danson R Rosell R Stahel P Thomas R M Rudd J Vansteenkiste N Thatcher C Manegold J-L Pujol N van Zandwijk C Gridelli J P van Meerbeeck L Crino A Brown P Fitzgerald M Aristides J H Schiller

PURPOSE Gemcitabine-platinum combination activity has been clearly established in a number of phase II studies. It has also been compared against other combinations in many phase III trials. It is generally believed that all such regimens have an equivalent impact on survival. This meta-analysis aims to quantify the treatment effect of gemcitabine plus a platinum agent in the treatment of advan...

Journal: :Dalton transactions 2014
Christelle Hureau Peter Faller

In the present Frontier article, we highlight recent new results on the use of platinoid complexes as therapeutic agents against Alzheimer's disease and infer the relevance of targeting monomeric soluble disordered amyloid peptides to preclude the deleterious aggregation process associated with the etiology of the disease.

Journal: :AJNR. American journal of neuroradiology 2007
D J Rivet C J Moran A Mazumdar T K Pilgram C P Derdeyn D T Cross

BACKGROUND AND PURPOSE This study was undertaken to analyze the outcomes and treatment-related complications of the polyglycolic/polylactic acid (PGLA)-coated Matrix platinum coils in the treatment of intracranial aneurysms and compare these results with those derived from the same single-institutional experience with use of uncoated, bare platinum coils. MATERIALS AND METHODS In this study, ...

Journal: :British journal of industrial medicine 1986
R D Murdoch J Pepys E G Hughes

All 306 South African platinum refinery workers (116 white, 190 coloured) accepted for employment on grounds of absence of evidence of atopy were investigated using the skin prick test and RAST to detect sensitivity to platinum, palladium, and rhodium salts. RAST studies were made for these, together with HSA and DNP-HSA RAST. Of the 306 workers, 38 had a positive skin prick test to the platinu...

Journal: :Acta biochimica et biophysica Sinica 2009
Jifeng Feng Xinchen Sun Ning Sun Shukui Qin Fan Li Hongyan Cheng Baoan Chen Yuandong Cao Jun Ma Lu Cheng Zuhong Lu Jiazhong Ji Yingfeng Zhou

DNA repair capacity (DRC) is correlated with sensitivity of cancer cells toward platinum-based chemotherapy. We hypothesize that genetic polymorphisms in DNA repair gene XPA (xeroderma pigmentosum group A) and XPG (xeroderma pigmentosum group G) (ERCC5, excision repair cross-complementation group 5), which result in inter-individual differences in DNA repair efficiency, may predict clinical res...

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