BACKGROUND Silver nanoparticles (AgNps) have attracted much interest in biomedical engineering, since they have excellent antimicrobial properties. Therefore, AgNps have often been considered for incorporation into medical products for skin pathologies to reduce the risk of contamination. This study aims at evaluating the antimicrobial effectiveness of AgNps stabilized by pluronic™ F68 associat...

We hypothesized that custom-designed microemulsions would effectively scavenge compounds from bulk media. Pluronic-based oil-in-water microemulsions were synthesized that efficiently reduced the free concentration of the local anesthetic bupivacaine in 0.9% NaCl. Both the molecular nature and concentration of the constituents in the microemulsions significantly affected extraction efficiencies....

This article provides a brief and basic discussion of Pluronic lecithin organogel to include its history, its components, its mechanism of action, the range of active pharmacological agents that can and cannot be incorporated into a Pluronic lecithin organogel, as well as important information for those pharmacists who compound Pluronic lecithin organogel.

Macro biomolecules are of vital importance in regulating the biofunctions organisms, which proteins (including peptides when mentioned below) and nucleic acids (NAs) most important. Therefore, these NAs can be applied as “drugs” to regulate from abnormal normal. Either for NAs, challenging thing is avoid biodegradation or physicochemical degradation before they reach targeted location, then fun...

The pharmaceutical area can present some opportunities for mechanical engineers to develop a vast type of dosage forms particularly novel forms like nanoparticles. The classical education of mechanics needs some alterations to prepare appropriate education courses in this regard. In order to present some views about this issue, we collect some information around the importance of mechanical eng...

Purpose: The aim of the present study was to formulate and evaluate miconazole nitrate containing thermosensitive bioadhesive gel for vaginal drug delivery to achieve a better therapeutic efficacy and patient compliance in the treatment for vaginal candidiasis. Method: Here miconazole nitrate (1%) was formulated as a vaginal gel using thermosensitive polymer, pluronic F127 (20%) along with bioa...