The shells of various poly(dl-lactide)-b-poly(acrylic acid) (PDLLA-b-PAA) spherical micelles and poly(l-lactide)-b-poly(acrylic acid) (PLLA-b-PAA) cylindrical micelles were functionalized with mannose to yield glyco-nanoparticles (GNPs) with different shapes and dimensions. All of these GNPs were shown to have good biocompatibility (up to 1 mg/mL). Cellular uptake experiments using RAW 264.7 ha...

The aim of this present study was to develop a pH sensitive interpenetrating polymeric network (IPN) hydro gels (HG) based on chitosan-acryl amide-grafted-poly ethylene glycol (CTS-AM-PEG) followed by hydrolysis that are cross-linked with glutaraldehyde (GA). Cefotaxime is an antibiotic drug was successfully loaded in these IPNHG’s. The HGs formed were characterized by Fourier transform infrare...

Fluorescence spectroscopy on a series of aqueous solutions of poly(acrylic acid) containing a luminescent label showed that polymers with molar mass, Mn < 16.5 kDa did not exhibit a pH responsive conformational change, which is typical of higher molar mass poly(acrylic acid). Below this molar mass, polymers remained in an extended conformation, regardless of pH. Above this molar mass, a pH-depe...

Intelligent soft biomimetic materials have been one of the focuses scientific research in recent years. However, designing and fabricating devices with multiple functions responses remains a considerable challenge. In this study, light humidity dual responsive actuator was prepared by incorporating light-sensitive liquid crystalline networks (LCNs) hydrophilic poly(2-carboxyethyl acrylate-co-ac...

Electrospun fibers of the thermo-and pH sensitive poly(N-vinylcaprolactam-co-acrylic acid) (Poly(NVCL-co-AA) loaded with 10% and 30 wt% caffeine (Caf) were obtained by electrospinning evaluated as potential drug delivery systems. Caffeine was used a hydrophilic model, poly(NVCL-co-AA) containing either 20 or mol% AA carrier. The morphology, well as, their interaction caffeine, studied using dif...

Bioactive glasses (BG) are used to regenerate bone, as they degrade and release therapeutic ions. Glass ionomer cements (GIC) are used in dentistry, can be delivered by injection, and set in situ by a reaction between an acid-degradable glass and a polymeric acid. Our aim was to combine the advantages of BG and GIC, and we investigated the use of alkali-free BG (SiO2–CaO–CaF2–MgO) with 0–50% of...

Composites in 25 kg batches were compounded of cellulose nanocrystals (CNC) and thermomechanical pulp (TMP) shaped into caps at industrial facilities on a pilot-plant scale. Some the material was also injection molded plaques to compare effect laboratory-scale pilot-scale compounding poly(ethylene-co-acrylic acid) (EAA7) poly(caprolactone) composites reinforced with 10 wt% CNC TMP. The material...